Some research is too risky to be conducted on anyone with a life expectancy of more than a few hours. Yet under some circumstances, the research can still be carried out by using subjects who are either brain dead or are soon to undergo a terminal wean, and who have articulated values that inclusion in the study can honor. So argues a team of ethicists and researchers at M.D. Anderson Cancer Center, where such research was recently undertaken.
Download full-text PDF |
Source |
---|
Semin Dial
December 2024
Department of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital, Hong Kong.
We report the successful application of single pass albumin dialysis (SPAD) and hemoadsorption (HA) in two teenagers with amlodipine poisoning. A 16-year-old girl with amlodipine overdose developed refractory shock and lactic acidosis despite multiple inotropes, calcium, insulin, and glucagon infusion. SPAD was initiated 18 h after the incident for 21 h.
View Article and Find Full Text PDFMedicina (B Aires)
December 2024
Clínica La Pequeña Familia, Junín, Buenos Aires, Argentina.
Western equine encephalitis is a zoonotic viral disease transmitted by the bite of an infected mosquito. Humans are terminal hosts and since they develop a very low and short lasting viremia, they are incapable of transmitting the disease. Most cases are asymptomatic, but it can present with high fever, myalgia and encephalitis or meningitis.
View Article and Find Full Text PDFInt J Dev Neurosci
December 2024
Graduate Program in Nutrition, Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.
J Clin Monit Comput
November 2024
Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.
This study investigated the clinical and physiological response to use of the BEACON Caresystem, a bedside open-loop decision support system providing advice to guide clinicians when weaning patients from invasive mechanical ventilation. Multicenter prospective study conducted in five adult intensive care units in the UK. Following screening and assent, intubated patients mechanically ventilated for > 24 h were randomized to intervention or usual care.
View Article and Find Full Text PDFEpilepsy Behav
December 2024
Epilepsy Center, Department of Neurology, University of Erlangen-Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany. Electronic address:
Burst suppression (BS) on EEG induced by intravenous anesthesia (IVAT) is standard therapy for refractory status epilepticus (RSE). If BS has any independent therapeutic effect on RSE is disputed. We aimed to define EEG characteristics of BS predicting termination or recurrence of status after weaning.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!