The authors, after examining two recent cases, explain a number of basic concepts regarding the diagnosis and therapy of Warthin's tumour of the parotid gland. Despite their low frequency, such tumours are very important because of their aetiopathogenesis, which is still controversial, and the recent increase in their incidence in females. Today, the diagnostic protocol, undertaken after the necessary clinical examination, relies mainly on ultrasonography and CT, but only a postoperative histological examination is capable of yielding a sure diagnosis and establishing the main histomorphological characteristics of the tumour. The therapeutic approach can be limited to conservative treatment, sparing the parotid gland and its vascularization and innervation.
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Acta Radiol
January 2025
Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China.
Background: Different parotid tumors differ in terms of treatment strategies due to their distinct biological behaviors. Time-dependent diffusion magnetic resonance imaging (t-dMRI) can characterize and quantify the cytological indexes, and then aid the differential diagnosis of various tumors. However, the value of t-dMRI in the analysis of parotid gland tumors remains unclear.
View Article and Find Full Text PDFStomatologiia (Mosk)
January 2025
Central Research Institute of Dentistry and Maxillofacial Surgery, Moscow, Russia.
Frey syndrome is a late complication after parotidectomy and represents an aberrant regeneration of the auricular nerve after its damage. The degree of manifestation can vary from minor hyperemia to the inability to eat in public places. As it turned out, the etiology of this syndrome is much broader than we might have assumed, as evidenced by the data of domestic and foreign literature.
View Article and Find Full Text PDFBackground: Currently, a majority of institution-specific automatic MRI-based contouring algorithms are trained, tested, and validated on one contrast weighting (i.e., T2-weighted), however their actual performance within this contrast weighting (i.
View Article and Find Full Text PDFGland Surg
December 2024
Department of Otolaryngology-Head and Neck Surgery, Sidney Kimmel Comprehensive Cancer Center-Jefferson Health Asplundh Cancer Pavilion, Willow Grove, PA, USA.
Various approaches and techniques have been developed to address parotid neoplasms over the years. This article reflects on the integration, modification, and refinement of these techniques over a decade of clinical practice. This article provides a narrative description of the evolution of a head and neck oncologic surgeon's approach to parotid neoplasms.
View Article and Find Full Text PDFOral Maxillofac Surg
January 2025
Oral Biology Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
Objective: A nanometer-sized vesicles originating from bone marrow mesenchymal stem cells (BMMSCs), called exosomes, have been extensively recognized. This study defines the impact of BMMSCs and their derived exosomes on proliferation, apoptosis and oxidative stress (OS) levels of CP-induced parotid salivary gland damage.
Methods: BMMSCs were isolated from the tibia of four white albino rats and further characterized by flowcytometric analysis.
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