The growth of cell populations of intercalated ducts (ID), striated ducts (SD) and convoluted granular tubules (CGT) of the submandibular gland of the mouse was analyzed, during the period of 14 to 84 days of postnatal life, by means of morphometric methods. The absolute number of cells in each type of duct was submitted to curve fitting by means of linear regression analysis, and the obtained equations were: y = 13.22 + 0.87x for ID cells in the growth period of 14 to 84 days; y = -18.82 + 3.69x and y = 176.03 - 1.93x for SD cells in the periods of growth and decay of cells, from 14 to 35 and 35 to 84 days, respectively; and y = 90.59 + 4.60x for CGT cells in the growth period of 28 to 84 days. Based on these equations, the daily accumulation (growth rate) or loss (decaying rate) of cells in the period covered by each equation was calculated. Thus, the rate of growth of ID cells was 0.87 x 10(5) cells/day; the growth and decline rates of SD cells were 3.69 x 10(5) cells/day and -1.93 x 10(5) cells/day, respectively; and the growth rate of CGT cells was 4.60 x 10(5) cells/day. The analysis of the accumulation or loss of cells and the balance of cell populations in the various types of ducts revealed that SD cells were transformed into CGT cells and that the growth of these cells population also depends on the formation of new cells through proliferative activity, probably in the intercalated ducts.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1590/s1517-74912002000400002 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Putative endothelial progenitor cells do not promote vascular repair but attenuate pericyte-myofibroblast transition in UUO-induced renal fibrosis.
Stem Cell Res Ther
March 2019
Departments of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan, 430030, Hubei, China.
Background: Putative endothelial progenitor cells (pEPCs) have been confirmed to participate in alleviation of renal fibrosis in several ischaemic diseases. However, their mechanistic effect on renal fibrosis, which is characterized by vascular regression and further rarefaction-related pathology, remains unknown.
Methods: To explore the effect and molecular mechanisms by which pEPCs act on unilateral ureteral obstruction (UUO)-induced renal fibrosis, we isolated pEPCs from murine bone marrow.
N-Acetyl-2-Aminofluorene (AAF) Processing in Adult Rat Hepatocytes in Primary Culture Occurs by High-Affinity Low-Velocity and Low-Affinity High-Velocity AAF Metabolite-Forming Systems.
Toxicol Sci
May 2018
Department of Pharmacology, School of Medicine, University of California, San Diego, La Jolla, California 92093.
N-acetyl-2-aminofluorene (AAF) is a procarcinogen used widely in physiological investigations of chemical hepatocarcinogenesis. Its metabolic pathways have been described extensively, yet little is known about its biochemical processing, growth cycle expression, and pharmacological properties inside living hepatocytes-the principal cellular targets of this hepatocarcinogen. In this report, primary monolayer adult rat hepatocyte cultures and high specific-activity [ring G-3 H]-N-acetyl-2-aminofluorene were used to extend previous observations of metabolic activation of AAF by highly differentiated, proliferation-competent hepatocytes in long-term cultures.
View Article and Find Full Text PDFImpact of a timed-release FSH treatment from 2 to 6 months of age in bulls II: Endocrinology, puberty attainment, and mature sperm production in Holstein bulls.
Theriogenology
January 2018
The Ohio State University, Department of Animal Science, Columbus, OH 43210, USA; University of Wyoming, Department of Animal Science, Laramie, WY 82071, USA. Electronic address:
The use of genomic testing in the cattle industries has renewed an interest in hastening bull puberty. In prepubertal males, FSH facilitates Sertoli cell proliferation and testis maturation. The aim of this study was to determine the effect of prepubertal administration of a timed-release FSH (delivered in a hyaluronan solution) on hormone secretion, puberty attainment, and mature sperm production in Holstein bulls in an AI center.
View Article and Find Full Text PDFPhysico-chemical and biological characterizations of two human prolactin analogs exhibiting controversial bioactivity, synthesized in Chinese hamster ovary (CHO) cells.
Protein Expr Purif
August 2006
Biotechnology Department, National Nuclear Energy Commission-IPEN-CNEN, Cidade Universitária, São Paulo, Brazil.
The synthesis, purification and characterization of G129R-hPRL and S179D-hPRL, the two better-studied antagonists of human prolactin (hPRL), is described. Both of these have been expressed for the first time, in their authentic form, by a stable CHO cell line, at secretion levels of 7.7 and 4.
View Article and Find Full Text PDFGrowth of cell populations of the intralobular duct in the submandibular gland of the mouse during postnatal development.
Pesqui Odontol Bras
May 2003
Department of Biological Sciences, School of Dentistry of Bauru, University of São Paulo, Brasil.
The growth of cell populations of intercalated ducts (ID), striated ducts (SD) and convoluted granular tubules (CGT) of the submandibular gland of the mouse was analyzed, during the period of 14 to 84 days of postnatal life, by means of morphometric methods. The absolute number of cells in each type of duct was submitted to curve fitting by means of linear regression analysis, and the obtained equations were: y = 13.22 + 0.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!