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| http://dx.doi.org/10.1136/thorax.58.3.189 | DOI Listing |
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The Diverse Roles of Long Non-Coding RNA HOTTIP in Breast and Gynecological Cancer Progression.
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Department of Laboratory, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Long non-coding RNAs (lncRNAs) play vital roles in the development and progression of various tumors through multiple mechanisms. Among these, HOTTIP (HOXA transcript at the distal tip) stands out as an intriguing candidate with diverse functions in several malignancies, including breast cancer and gynecologic cancers such as ovarian, cervical, and endometrial cancers, which are significant global health concerns. HOTTIP interacts with key signaling pathways associated with these cancers, including Wnt/β-catenin, PI3K/AKT, and MEK/ERK pathways, enhancing their activation and downstream effects.
View Article and Find Full Text PDFCo-ensiling pomegranate (Punica granatum L.) peels and molasses with berseem (Trifolium alexandrinum L.) alters fermentation quality, nutrient composition, ruminal fermentation and methane production in buffalo bulls in-vitro.
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Pomegranate peels are an industrial by-product high in sugar and phytochemical content and pose an environmental concern. Meanwhile, ensiling legume forage such as berseem is difficult due to its lower dry matter content and water-soluble carbohydrate-to-buffering capacity ratio, which leads to a poor fermentation process. To date, no studies have been conducted to investigate the effect of co-ensiling pomegranate peels with berseem.
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Division of Gastroenterology, University of California, San Francisco, San Francisco, CA, USA.
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View Article and Find Full Text PDFLeveraging milk mid-infrared spectroscopy to authenticate animal welfare, farming practices, and dairy systems of Parmigiano Reggiano cheese.
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View Article and Find Full Text PDFThe effects of childhood maltreatment and social support on the trajectories of depressive symptoms from adolescence to young adulthood.
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Clarkson University, Potsdam, NY. USA.
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