Objective: To study effect of nimodipine (ND) on cochlear blood flow (CBF).
Method: CBF was measured in twenty-two guinea pigs by laser Doppler flowmetry(LDF).
Result: Nimodipine decreased CBF following the decrease of systemic BP and present a dose dependent mode, neither the dose of nimodipine is lower, normal and higher, nor the animal is under the status of normal supply of inner ear blood flow and ischemia of inner ear caused by vertebrobasilar insufficiency(VBI).
Conclusion: It suggested that this compound may be of little clinical use to elevate CBF.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
blood flow
12
nimodipine cochlear
8
cochlear blood
8
inner ear
8
[effects nimodipine
4
flow normal
4
normal vertebrobasilar
4
vertebrobasilar insufficiency
4
insufficiency status]
4
status] objective
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!