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Clinical and radiographic assessment of effect of platelet-rich fibrin on dental implant osseointegration - A split mouth randomized clinical trial.
J Prosthodont
January 2025
Department of Conservative Dentistry and Endodontics, Sri Ramachandra Dental College and Hospital, Chennai, India.
Purpose: Biomimetic agents are being researched for their potential to stimulate bone formation and boost bone-implant contact. The objective of this study was to assess how osseointegration of dental implants is impacted by platelet-rich fibrin.
Materials And Methods: The present study was a randomized clinical trial with a split mouth design.
Association Between Serum Antinuclear Antibody and Polycystic Ovarian Syndrome in Reproductive Women Aged 18 to 35 Years: A Quest for an Autoimmune Marker.
Cureus
December 2024
Obstetrics and Gynaecology, All India Institute of Medical Sciences, Raipur, IND.
Introduction: Polycystic ovarian syndrome (PCOS) is a heterogeneous endocrinal physiological disorder characterized by chronic oligo-ovulation or an-ovulation, hyperandrogenism, and polycystic morphology in ovaries on transvaginal or abdominal ultrasound. Hyperandrogenism and insulin resistance are already well-documented pathophysiological mechanisms in PCOS. Besides this, autoimmunity has been hypothesized in its pathogenesis.
View Article and Find Full Text PDFPrognostic value of [F]FDG PET/CT in patients with idiopathic pulmonary fibrosis.
Sci Rep
January 2025
Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
The study investigates the prognostic value of [F]fluorodeoxyglucose (FDG) PET/CT in patients with idiopathic pulmonary fibrosis (IPF). A total of 346 IPF patients who underwent FDG PET/CT between 2007 and 2020 were analyzed. Pulmonary FDG uptake [target to background ratio (TBR)] was binarized by optimal cut-off value based on survival analysis.
View Article and Find Full Text PDFConsensus Preconception Educational Domains for People With Mobility Disabilities: A Delphi Study.
Womens Health Issues
December 2024
Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Women's Research Institute, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania. Electronic address:
Background: Preconception health education is critical to improve pregnancy and neonatal outcomes, but people with mobility disabilities have specific, often unique issues related to preparing for pregnancy. This study sought to develop consensus-based domains for a preconception education curriculum for people with mobility disabilities.
Methods: We used a mixed methods approach, including a literature review and a Delphi method to develop consensus.
Adjusting for principal components can induce collider bias in genome-wide association studies.
PLoS Genet
December 2024
Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.
Principal component analysis (PCA) is widely used to control for population structure in genome-wide association studies (GWAS). Top principal components (PCs) typically reflect population structure, but challenges arise in deciding how many PCs are needed and ensuring that PCs do not capture other artifacts such as regions with atypical linkage disequilibrium (LD). In response to the latter, many groups suggest performing LD pruning or excluding known high LD regions prior to PCA.
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