Purpose: To determine whether weight at birth is related to prenatal exposure to persistent organochlorine compounds.
Methods: Birth weight was obtained for 197 singleton infants drawn from the general population born in two cities in Ukraine in 1993 to 1994. Concentrations of seven organochlorine pesticides (p,p'-DDT, p,p'-DDE, beta-hexachlorocyclohexane, hexachlorobenzene, trans-nonachlor, oxychlordane, heptachlor epoxide) and 11 polychlorinated biphenyl congeners measured in maternal milk taken at four or five days after birth were used as an index of prenatal exposure.
Results: The greatest differences were seen for beta-hexachlorocyclohexane, with a pattern not suggestive of dose-response; infants in the lowest tertile were small, those in the central tertile were large, and those in the upper tertile were average. Adjustment for gestational age and other potential confounders had little effect on these patterns. Infants in the two upper tertiles for p,p'-DDE were larger than those in the lower tertile, with the effect being more striking after adjustment for gestational age. Adjustment for potential confounders made the pattern disappear. Other chemicals showed no convincing evidence of effects.
Conclusions: Prenatal exposure to the chemicals studied, at concentrations currently seen in this population, does not impact weight at birth.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s1047-2797(02)00268-5 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Potential bacterial resources for bioremediation of organochlorine pesticides and flame retardants recognized from forest soil across China.
J Hazard Mater
December 2024
The Key Lab of Pollution Control and Ecosystem Restoration in Industry Clusters, Ministry of Education, School of Environment and Energy, South China University of Technology, Guangzhou, Guangdong 510006, PR China.
Microbe-mediated remediation becomes a desire method for removal of persistent organic pollutants (POPs) due to its eco-friendly and sustainable nature. The improvement of practical feasibility requires constructing comprehensive species pool, while it is still limited by the rapid recognition of potential bacterial resources from environment. Here, based on the relative abundances of bacterial OTUs and pollutant concentrations, we established indexes to assess their tolerance to organochlorine pesticides (OCPs) and flame retardants (FRs) that are atmospheric transported and naturally accumulated in forest soil via forest filter effect.
View Article and Find Full Text PDFPersistent organic pollutants and endogenous sex-related hormones in Hispanic/Latino adults: The Hispanic Community health study/study of Latinos (HCHS/SOL).
Environ Res
December 2024
Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois Chicago, USA.
Background: Previous studies have demonstrated associations of persistent organic pollutants (POPs) with sex-related hormones; however, findings were inconsistent. Sex-specific impacts and pathways through which adiposity influences associations are not completely understood. We sought to evaluate sex-specific associations of POPs serum concentration with sex-related hormones and to explore pathways through which adiposity may modify associations.
View Article and Find Full Text PDFTwo Hits of EDCs Three Generations Apart: Evaluating Multigenerational Anxiety-Like Behavioral Phenotypes in Male Rats Exposed to Aroclor 1221 and Vinclozolin.
Environ Health Perspect
December 2024
Division of Pharmacology & Toxicology, The University of Texas at Austin, Austin, Texas, USA.
Background: Increasing evidence supports an association of endocrine-disrupting chemical (EDC) exposures with adverse biological effects in humans and wildlife. Recent studies reveal that health consequences of environmental exposures may persist or emerge across generations. This creates a dual conundrum: that we are exposed to contemporary environmental chemicals overlaid upon the inheritance of our ancestors' exposure profiles.
View Article and Find Full Text PDFAtmospheric Aggravation Potential of a Wastewater Treatment Plant Concerning Organochlorine Pesticides, Polychlorinated Biphenyls, and Polybrominated Diphenyl Ether Emissions.
Chemosphere
December 2024
Bursa Technical University, Department of Environmental Engineering, Bursa, Türkiye. Electronic address:
The pollution potential of a municipal wastewater treatment plant (WWTP) in Bursa, Türkiye, in terms of organochlorine pesticides (ΣOCPs), polychlorinated biphenyls (ΣPCBs), and polybrominated diphenyl ethers (ΣPBDEs), was investigated in air samples. Concentrations were determined using polyurethane foam disk samplers at key processes, such as the aeration tank (AT) and settling chamber (SC) of the WWTP and the background area (BA) at an urban site. Atmospheric concentration levels of PBDEs at the SC are 1.
View Article and Find Full Text PDFOcean as source or sink for legacy persistent organic pollutants.
J Hazard Mater
December 2024
College of Oceanography and Ecological Science, Shanghai Ocean University, Shanghai 201306, China.
With the phase-out of legacy persistent organic pollutants (POPs), the ocean's role is evolving, potentially acting as both a reservoir and a source. This study investigates the air-sea fluxes of the first banned POPs, such as organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs), using literature from Web of Science up to 2023. OCP and PCB concentrations in air and seawater show significant spatiotemporal variability.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!