Solution-phase parallel synthesis of carbamates using polymer-bound N-hydroxysuccinimide.

Org Lett

Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Katahira, Aoba, Sendai, 980-8577 Japan.

Published: October 2002

[formula: see text] A convenient method for the synthesis of carbamates using polymer-supported N-hydroxysuccinimide is described. Various carbamates were synthesized in highly pure form without the need for chromatographic purification. This new "catch and release"-type solid-phase synthesis should be useful for combinatorial synthesis of various carbamates.

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http://dx.doi.org/10.1021/ol026756fDOI Listing

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