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Enhanced Transepithelial Riboflavin Delivery Across the Cornea Using Magnetic Nanocarriers.
J Ocul Pharmacol Ther
January 2025
Department of Analytical Chemistry, Faculty of Pharmacy, Ankara Medipol University, Ankara, Turkey.
Keratoconus is a progressive corneal ectasia characterized by irregular astigmatism, leading to corneal scarring and decreased vision. Corneal cross-linking (CXL) is the standard treatment to halt disease progression, but its effectiveness in transepithelial (epithelium-on, epi-on) approaches is limited by the low permeability of the corneal epithelium to riboflavin (Rb). This study aimed to enhance transepithelial Rb penetration in bovine corneas using Rb-modified tannic acid-coated superparamagnetic iron oxide nanoparticles (Rb-TA-SPIONs) under an external magnetic field.
View Article and Find Full Text PDFBlood meal analysis: unveiling the feeding preferences of Aedes aegypti and Aedes albopictus in a dengue-endemic area.
Trop Biomed
December 2024
Department of Parasitology, Faculty of Medicine, Center of Insect Vector Study, Chiang Mai University, Chiang Mai, Thailand.
Studies have suggested animals as possible reservoir hosts for flaviviruses transmitted by Aedes mosquitoes; however, there is limited evidence for the dengue virus in Malaysia. One of the possible ways to determine the zoonotic potential for any pathogen transmission is through blood meal analysis which can provide valuable insights into the feeding preferences of the mosquitoes. Unfortunately, limited information is available on the feeding preferences of Aedes mosquitoes in Malaysia.
View Article and Find Full Text PDFThe impact of customized surface topography and porosity created by additive manufacturing technology on gingival fibroblasts.
J Prosthodont
January 2025
Prosthodontist, Implant Dentistry Associates of Arlington, Arlington, Texas, USA.
Purpose: The purpose of this study was to analyze gingival fibroblast proliferation on additively manufactured polymethylmethacrylate (PMMA) groups with different surface characteristics namely no treatment group (NTG) and customized 250 µm diameter porosity (AM-250G) group.
Materials And Methods: 3D-printed NTG was compared for its influence on growth of cells to a additively manufactured surface with porosity (AM-250G). For each group (NTG, AM-250G) 20 samples of material were tested.
Stabilization of blackberry extract by interaction with bovine sodium caseinate in the presence of tara gum.
J Sci Food Agric
January 2025
Laboratorio de Investigación, Desarrollo y Evaluación de Alimentos (LIDEA), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario (UNR), Santa Fe, Argentina.
Background: The antioxidant capacity of anthocyanins (AC) rapidly degrades during storage, highlighting the need for their stabilization. The conformational properties and high proline content of sodium caseinate (NaCAS), combined with the formation of NaCAS microgels in the presence of tara gum (TG) and acid gelation, suggest its potential as an effective stabilizing or encapsulating agent of AC.
Results: Spectrofluorimetric results suggest the formation of a complex between NaCAS and AC.
Effects of endometrial embryokines on the preimplantation bovine embryo to create a gene expression signature consistent with a high competence phenotype†.
Biol Reprod
January 2025
Department of Animal Sciences, University of Florida, Gainesville, FL 32611-0910, USA.
Optimal embryonic development depends upon cell-signaling molecules released by the maternal reproductive tract called embryokines. Identity of specific embryokines that enhance competence of the embryo for sustained survival is largely lacking. The current objective was to evaluate effects of three putative embryokines in cattle on embryonic development to the blastocyst stage.
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