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A puzzling malignant adrenal tumor.
Ann Endocrinol (Paris)
December 2024
Department of Endocrinology, Santo António Local Health Unit, Largo Professor Abel Salazar, 4099-001 Porto, Portugal.
A previously healthy 49-year-old male presented with abdominal pain, constitutional syndrome, paroxysmal palpitations and diaphoresis. Full-body CT scan showed a large malignant adrenal mass with abdominal lymph node and pulmonary metastasis. Biochemical studies revealed hypersecretion of catecholamines, cortisol, sexual steroids and steroid precursors; ACTH was not suppressed, and chromogranin A was negative.
View Article and Find Full Text PDFSynchronous ipsilateral adrenal cortical adenoma and ganglioneuroma: A case report.
Indian J Urol
September 2023
Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Synchronous tumors comprising of cortical as well as medullary differentiation are rare in the adrenal gland. Collision tumors comprise of two independent neoplasms arising from the cortex and the medulla without any histological admixture. Adrenal cortico-medullary mixed tumors are rare tumors comprising of adrenal cortical and chromaffin cells intermixed with each other.
View Article and Find Full Text PDFMixed Corticomedullary Tumor of the Adrenal Gland: A Case Report and Literature Review.
Medicina (Kaunas)
August 2023
Saint Vincent Hospital, 123 Summer Street, Worcester, MA 01608, USA.
Adrenal mixed corticomedullary tumors (MCMTs) are composed of an admixture of cortical and medullary cells. Owing to the presence of two distinct components of different embryonic lineage, these tumors are extremely rare. Less than 30 tumors of this type have been reported to date.
View Article and Find Full Text PDFCorticomedullary Mixed Tumor of the Adrenal Gland with Apparent F-Fluorodeoxyglucose Activity But No GA-DOTATATE Uptake on Positron Emission Tomography/Computed Tomography.
Indian J Nucl Med
November 2022
Department of Nuclear Medicine, Marmara University, Pendik Training and Research Hospital, Istanbul, Turkey.
Corticomedullary mixed tumor (CMT) is a single adrenal tumor mass composed histologically by an admixture of adrenal cortical and medullary cells. It is a rare condition, with approximately 20 cases reported to date. To our knowledge, the positron emission tomography (PET) imaging findings of this mostly benign tumor have not been reported in the literature.
View Article and Find Full Text PDFA Rare Case: Adrenal Corticomedullary Mixed Tumor With Elements of Pheochromocytoma, Cortical Adenoma, and Ganglioneuroma Cells.
AACE Clin Case Rep
December 2022
Division of Endocrinology and Metabolism, Cedars-Sinai Medical Center, Los Angeles, California.
Background/objective: Adrenal corticomedullary mixed tumor (CMMT) are extremely rare single adrenal tumor masses containing a mixture of adrenal cortical adenoma and pheochromocytoma cells.
Case Report: A 52-year-old woman presented with clinical and biochemical evidence of cortisol and catecholamine excess and was found to have an adrenal CMMT with intermixed chromaffin, cortical adenoma, and ganglioneuroma components. She underwent a successful unilateral adrenalectomy with subsequent improvement in her symptoms.
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