Disabling overactivity of the extensor hallucis longus after stroke: clinical expression and efficacy of botulinum toxin type A.

Arch Phys Med Rehabil

Physical Medicine and Rehabilitation Department, GH Lariboisière-Fernand Widal, Paris, France.

Published: January 2003

Objectives: To describe the clinical characteristics of persistent extension of the great toe related to overactivity of the extensor hallucis longus (EHL) after a stroke and to explore the efficacy of treatment with botulinum toxin type A.

Design: Case series.

Setting: A physical medicine and rehabilitation department in France.

Participants: Eleven patients with hemiplegia disabled by overactivity of the EHL were classified according to the different ways in which that overactivity was triggered. Disability was related to pain in 5 patients, to shoe difficulties in 10 patients, and to varus foot in 6 patients.

Intervention: Injection of botulinum toxin type A into the EHL.

Main Outcome Measures: Efficacy was assessed on day 15 by triggering of pain, shoe difficulties, and varus deformity and by patients' subjective assessment on day 15, at 3 months, and at 6 months.

Results: On day 15, EHL overactivity disappeared after 16 of the 18 injections in 10 patients; subjective assessment was very good for pain and shoe difficulties and remained good or very good at 3 months for 8 patients who received 12 injections.

Conclusion: Botulinum toxin type A is effective in treating disability related to poststroke overactivity of the EHL.

Download full-text PDF

Source
http://dx.doi.org/10.1053/apmr.2003.50077DOI Listing

Publication Analysis

Top Keywords

botulinum toxin
16
toxin type
16
shoe difficulties
12
overactivity extensor
8
extensor hallucis
8
hallucis longus
8
overactivity ehl
8
pain shoe
8
subjective assessment
8
overactivity
5

Similar Publications

Introduction: Giant omphalocele poses a conflict between eviscerated content and abdominal capacity, with associated risks such as compartment syndrome or cardiovascular compromise.

Clinical Case: We present the case of a prenatally diagnosed hepato-omphalocele, without associated abnormalities. At week 37, botulinum toxin was injected in the right hemiabdomen under fetal and maternal sedation.

View Article and Find Full Text PDF

Brachial Plexus Birth Injury: Treatment and Interventions.

Plast Surg (Oakv)

January 2025

Division of Plastic and Reconstructive Surgery, Saint Louis University Hospital, St. Louis, MO, USA.

Brachial plexus birth injury (BPBI) is a condition affecting newborns and involves damage to the nerve fibers compromising the brachial plexus during birth. Although most newborns recover spontaneously, a large subset require surgery to regain function, and others will have permanent disability despite intervention. Deciding when to pursue surgical intervention remains a challenge for clinicians treating BPBI.

View Article and Find Full Text PDF

Palmar hyperhidrosis is common condition that is challenging to treat. Nonsurgical treatments include topical antiperspirants, iontophoresis, anticholinergic drugs and botulinum toxin injections. To evaluate the safety and efficacy of ablative fractional laser therapy, combined with topically applied botulinum toxin versus its injection for the treatment of hyperhidrosis.

View Article and Find Full Text PDF

Botulinum toxin (BoNT) has traditionally been utilized to relieve tension in muscular and connective tissue diseases (CTD). However, its usage has rapidly expanded and now encompasses usage for neurological, gastrointestinal, psychological, cardiovascular, ophthalmology, orthopedics, and more. More recently, its usage has been utilized for sequelae of CTDs such as Raynaud's disease and reduced oral aperture secondary to scleroderma/systemic sclerosis.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!