Sources of errors in determination of hemoglobin were found out. The results were demonstrated to have comparison hemoglobin determination by hemiglobincyanide and hemichrome methods; this or that set of agents is of no significant advantage; to properly determine hemoglobin in the blood it is important to have calibration specimens and high quality control hemoglobin solutions; the equipment in use should be checked and calibrated; calibration hemiglobincyanide specimens produced at SPA "Renam". "Bak. preparations" and hemichrome specimens produced at JSC "Vector-Best" provide high precision of hemoglobin determination; the results of hemoglobin determination in control solutions obtained in autoanalyzers and manually, are comparable.

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