Background: Gastric electrical activity can be accurately recorded and analyzed by cutaneous electrogastrography. Different types of abnormalities have been described in a variety of disorders.

Aim: To analyze a group of asymptomatic subjects and assess the prevalence and patterns of dysrrhythmias in patients with type 1 and 2 diabetes and patients with functional dyspepsia.

Patients And Methods: One hundred subjects were studied (32 male, mean age 45 years old, 10 asymptomatic, 11 type 1 diabetics, 22 type 2 diabetics and 57 subjects with functional gastrointestinal disturbances). Gastric myoelectrical activity was recorded using surface electrogastrography for 1 hour in the fasting state and 1 hour after a test meal (350 kcal).

Results: The electrogastrogram was normal in 90% of asymptomatic controls. It was abnormal in 64% of type 1 diabetic patients, in 55.5% of type 2 diabetic patients and in 61% of patients with functional dyspepsia. Different types of dysrrhythmias were observed in each group.

Conclusions: Electrogastrography might define a subgroup of patients with electrical rhythm disturbances, that may have a different approach to treatment than patients with normal gastric electrical activity.

Download full-text PDF

Source

Publication Analysis

Top Keywords

gastric electrical
8
electrical activity
8
patients functional
8
type diabetics
8
type diabetic
8
diabetic patients
8
patients
7
type
5
[cutaneous electrogastrography
4
electrogastrography incorporated
4

Similar Publications

Protocol for applying Tumor Treating Fields in mouse models of cancer using the inovivo system.

STAR Protoc

January 2025

Department of Medicine, Division of Hematology, Oncology, and Transplantation, University of Minnesota Medical School, Minneapolis, MN, USA; Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, MN, USA. Electronic address:

Tumor Treating Fields (TTFields) are electric fields clinically approved for cancer treatment, delivered via arrays attached to the patient's skin. Here, we present a protocol for applying TTFields to torso orthotopic and subcutaneous mouse tumor models using the inovivo system. We guide users on proper system component connections, study protocol design, mouse fur depilation, array application, and treatment condition adjustment and monitoring.

View Article and Find Full Text PDF

Signature of collagen alpha-1(x) gene expression in human cancers and their therapeutic implications.

Pathol Res Pract

January 2025

Department of Electric and Electronic Engineering, Dr. M.G.R Educational and Research Institute, Deemed to Be University, Chennai, Tamil Nadu 600 095, India.

Cancers are a class of disorders that entail uncontrollably unwanted cell development with dissemination. One in six fatalities globally is attributed to cancer, a global health issue. The analysis of the entire DNA sequence and how it expresses itself in tumor cells is known as cancer genomics.

View Article and Find Full Text PDF

Attenuates 5-Fluorouracil-Induced Intestinal Mucositis in Mice.

Pharmaceuticals (Basel)

December 2024

Laboratory of Gastrointestinal Physio-Pharmacology (LEFFAG), Federal University of Ceará, Coronel Nunes de Melo Street, 1315 Rodolfo Teófilo, Fortaleza 60416-030, CE, Brazil.

5-Fluorouracil (5-FU) is an antimetabolite widely prescribed in cancer treatments, but its use in highly proliferative tissues can cause significant problems such as mucositis. is a probiotic commonly used for protection against acute diarrhea, gastrointestinal dysbiosis and inflammatory bowel diseases. We investigated the effect of on 5-FU intestinal mucositis in mice.

View Article and Find Full Text PDF

Interstitial cells of Cajal in the plane of the myenteric plexus (ICC-MY) serve as electrical pacemakers in the stomach and small intestine. A similar population of cells is found in the colon, but these cells do not appear to generate regular slow wave potentials, as characteristic in more proximal gut regions. Ca handling mechanisms in ICC-MY of the mouse proximal colon were studied using confocal imaging of muscles from animals expressing GCaMP6f exclusively in ICC.

View Article and Find Full Text PDF

Magnetic Resonance Imaging of Gastric Motility in Conscious Rats.

Neurogastroenterol Motil

December 2024

Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.

Introduction: Gastrointestinal (GI) magnetic resonance imaging (MRI) enables simultaneous assessment of gastric peristalsis, emptying, and intestinal filling and transit. However, GI MRI in animals typically requires anesthesia, which complicates physiology and confounds interpretation and translation to humans. This study aimed to establish GI MRI in conscious rats, and for the first time, characterize GI motor functions in awake versus anesthetized conditions.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!