The study included 622 persons of the third age, 60-94 years old. The subjects were analyzed by age, smoking habits, profession and place of longest residence. In the studied group, there were 27.2% men smokers and 12.6% women smokers. In relation to profession, women were mostly office employees (35.4%) and men were mostly workers (46.9%). Ventilatory capacity was measured by recording maximum expiratory flow-volume on which forced vital capacity (FVC), one second forced expiratory volume (FEV1), and maximum expiratory flow rates at 50% and the last 25% of vital capacity were read (FEF50' FEF25). All respiratory symptoms were significantly more prevalent in smokers than in nonsmokers. The highest prevalence was found for chronic cough in men (31.1%) and in women (30.1%) as well as for dyspnea in women (54.7%) and in men (43.5%). A higher prevalence of respiratory symptoms was found in the age group 60-69 years old than in subjects older than 70 years. Asthma was more prevalent in workers and farmers, which is probably the result of work exposure. Logistic regression analysis of chronic respiratory symptoms and diseases in older men and women by profession, age, place of longest residence and smoking habits did not show statistically significant difference between effects of those variables on the development of respiratory symptoms and disease. The measured values of ventilatory capacity tests were decreased up to 70-79 years of age. After that there is no decrease expressed as a percentage of reference values.
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J Med Virol
January 2025
Department of Morphology and Genetics, Federal University of São Paulo, São Paulo-SP, Brazil.
We identified seven distinct coronaviruses (CoVs) in bats from Brazil, classified into 229E-related (Alpha-CoV), Nobecovirus, Sarbecovirus, and Merbecovirus (Beta-CoV), including one closely related to MERS-like CoV with 82.8% genome coverage. To accomplish this, we screened 423 oral and rectal swabs from 16 different bat species using molecular assays, RNA sequencing, and evolutionary analysis.
View Article and Find Full Text PDFAnn Med
December 2025
Department of Clinical Pharmacology, Flinders Medical Centre, Southern Adelaide Local Health Network, Adelaide, Australia.
Background: Most older patients with atrial fibrillation (AF) have comorbidities. However, it is unclear whether specific comorbidity patterns are associated with adverse outcomes. We identified comorbidity patterns and their association with mortality in multimorbid older AF patients with different multidimensional frailty.
View Article and Find Full Text PDFZhongguo Dang Dai Er Ke Za Zhi
January 2025
Department of Respiratory Medicine, Children's Hospital of Chongqing Medical University/National Clinical Research Center for Child Health and Disorders /Ministry of Education Key Laboratory of Child Development and Disorders/Chongqing Key Laboratory of Pediatrics, Chongqing 400014, China.
Children with bronchopulmonary dysplasia (BPD) often exhibit severe respiratory problems and significant pulmonary dysfunction during school age and adulthood. Exercise tests show a decline in cardiopulmonary function and physical performance in children with BPD, who also have a higher incidence of pulmonary hypertension. These children generally perform poorly in terms of intelligence, language, and motor development.
View Article and Find Full Text PDFJ Coll Physicians Surg Pak
January 2025
Department of Dermatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
Sweet syndrome, also known as acute febrile neutrophilic dermatosis, is a rare condition characterised by fever, leucocytosis, and painful skin lesions. This retrospective study analysed 21 patients with Sweet syndrome treated at the Affiliated Hospital of Xuzhou Medical University from January 2015 to June 2022. The study aimed to investigate the aetiology, clinicopathological features, and treatment outcomes.
View Article and Find Full Text PDFCrit Care
January 2025
Department of Intensive Care Unit, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Background: Despite the physiological advantages of positive end-expiratory pressure (PEEP), its optimal utilization during one-lung ventilation (OLV) remains uncertain. We aimed to investigate whether individualized PEEP titration by lung compliance is associated with a reduced risk of postoperative pulmonary complications during OLV.
Methods: We searched PubMed, Embase, and the Cochrane Central Register of Controlled Trials until April 1, 2024, to identify published randomized controlled trials that compared individualized PEEP titration by lung compliance with fixed PEEP during OLV.
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