The experience is submitted gained with the diagnosis and treatment of Chlamydia trachomatis-associated esophagitis. Used in the study were laboratory and instrumental methods of diagnosis, with their merits and demerits outlined. It is pointed out that complex diagnosis of Chlamydia trachomatis-produced esophagitis is important, the treatment involving institution of anti-bacterial and immunomodulating therapies.
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Chlamydiosis is one of the main causes of the progressive decline of koala populations in eastern Australia. While histologic, immunologic, and molecular studies have provided insights into the basic function of the koala immune system, the immune cell signatures during chlamydial infection of the reproductive tract in koalas have not been investigated. Thirty-two female koalas and 47 males presented to wildlife hospitals with clinical signs suggestive of infection were euthanized with the entire reproductive tract collected for histology; immunohistochemistry (IHC) for T-cell (CD3ε, CD4, and CD8α), B-cell (CD79b), and human leukocyte antigen (HLA)-DR markers; and quantitative real-time polymerase chain reaction (rtPCR) for .
View Article and Find Full Text PDFTheriogenology
September 2022
School of Veterinary Science, The University of Queensland, Gatton, 4343, Australia.
Infection with Chlamydia pecorum is one of the main causes of progressive decline of koala (Phascolarctos cinereus) populations in Eastern Australia. Pathological changes associated with the chlamydial infection in the genital tract of female and male koalas have been widely described with reports of acute and chronic lymphoplasmacytic inflammation and the description of the cystic dilatation of the ovarian bursa. Although these disease manifestations can result in severe chronic inflammation, structural changes and even sterility, only limited data is currently available on the organism's distribution and associated histopathological and ultrastructural changes within the upper genital tract of affected females.
View Article and Find Full Text PDFAvian Dis
June 2020
Turlock Branch, University of California, Davis, California Animal Health & Food Safety Laboratory System, Turlock, CA 95380,
J Wildl Dis
January 2020
School of Agriculture and Food Sciences, University of Queensland, Gatton, Queensland 4343, Australia.
Declining population sizes of koalas () in SE Queensland (QLD), Australia can partially be attributed to chlamydiosis, with the majority of epidemiological studies focusing on the prevalence of infection and associated pathology in female koalas, with lesser attention given to males. We aimed to explore the epidemiology of infection in the male urogenital tract from wild (hospitalized and free-ranging) koalas in SE QLD. Although 67% of male koalas were infected with in their urogenital tract and 55% were shedding the organism in their semen, only a third of the males sampled presented with overt signs of urogenital disease.
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