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Pd.Et3B-catalyzed alkylation of amines with allylic alcohols. | LitMetric

Pd.Et3B-catalyzed alkylation of amines with allylic alcohols.

Chem Commun (Camb)

Department of Applied Chemistry, Faculty of Engineering, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.

Published: January 2003

A combination of catalytic amounts of Pd (0.05 mmol) and Et3B (0.3 mmol) promotes allylic alkylation of primary and secondary aromatic and aliphatic amines (1.0 mmol) by the direct use of allylic alcohols, providing tertiary amines in excellent yields under mild conditions (room temperature approximately 50 degrees C).

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Source
http://dx.doi.org/10.1039/b210920dDOI Listing

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