AI Article Synopsis
- The study investigates how electro-acupuncture (EA) affects calcium (Ca2+) levels in rat brain cells during focal cerebral ischemia.
- Initial observations show that Ca2+ levels remain stable in the cerebral cortex for the first hour of ischemia but increase significantly in the striatum after three hours, with striatum levels being notably higher.
- Treatment with EA for 30 minutes after three hours of ischemia significantly reduces the elevated Ca2+ content, suggesting that EA may help protect neurons from damage caused by ischemia.
Article Abstract
Objective: To study the effect of electro-acupuncture (EA) in regulating calcium (Ca2+) content in brain neurocytes of rats with focal cerebral ischemia.
Methods: The changes of Ca2+ content in ischemic neurocytes were observed by using laser confocal scanning microscope.
Results: Ca2+ content did not change significantly in cerebral cortex when the brain ischemia occurred for 1 hr, but it raised significantly in striatum neurocytes. Both the Ca2+ contents in striatum and cortex area increased significantly 3 hrs after ischemia occurrence and the content in striatum was higher than that in cortex significantly. Brain Ca2+ content could be reduced significantly after the 3 hrs ischemic brain were treated by EA for 30 min.
Conclusion: EA could regulate the content of Ca2+ in the ischemic area of brain, inhibit Ca2+ overload, so as to protect neurons from ischemic injury.
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