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Analysis of Platelet Morphological Parameters as Clinical Risk Stratification in Acute Coronary Syndrome.
Catheter Cardiovasc Interv
January 2025
Department of Cardiology, The Second Hospital of Shandong University, Jinan, Shandong, People's Republic of China.
Background: Platelet activation plays a central role in the pathogenesis of acute coronary syndrome (ACS). Platelet morphological parameters, including MPV, PDW, and P-LCR, are emerging as biomarkers for predicting the severity of ACS and prognosis.
Aims: This study aims to assess the relationship between these parameters and coronary severity and to evaluate their predicting adverse outcomes.
Under an adaptive hypothesis, the reciprocal influence between mutualistic plants and frugivores is expected to result in suites of matching frugivore and plant traits that structure fruit consumption. Recent work has suggested fruit traits can represent adaptations to broad groups of functionally similar frugivores, but the role of frugivore traits and within-species variation in structuring fruit consumption is less understood. To address these knowledge gaps, we assess the presence of reciprocal trait matching for the mutualistic ecological network comprising of bats that feed on and disperse seeds.
View Article and Find Full Text PDFUnlabelled: The deubiquitinating enzyme BAP1, the catalytic subunit of the PR-DUB complex, is implicated in several cancers, in the familial cancer syndrome BAP1 Tumor Predisposition Syndrome, and in the neurodevelopmental disorder Küry -Isidor syndrome. In there are numerous reports in the literature describing developmental patterning phenotypes for several chromatin regulators including the discovery of Polycomb itself, but corresponding adult morphological phenotypes caused by developmental dysregulation of ortholog ( ) are less well-described. We report here that knockdown of in the eye and wing produce concomitant chromatin dysregulation phenotypes.
View Article and Find Full Text PDFReference genome of Calochortus tolmiei Hook. & Arn. (Liliaceae), a cat's ear mariposa lily.
G3 (Bethesda)
January 2025
School of Integrative Plant Science, Section of Plant Biology and the L.H. Bailey Hortorium, Cornell University, Ithaca NY 14853 USA.
Calochortus tolmiei Hook. & Arn., a bulbous monocot with cat's ear flowers in the angiosperm family Liliaceae, is a perennial herb native to northern California, Oregon, and Washington.
View Article and Find Full Text PDFCortisol regulates neonatal lung development via Smoothened.
Respir Res
January 2025
National Clinical Research Center for Aging and Medicine, State Key Laboratory of Medical Neurobiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Background: Neonatal respiratory distress syndrome (NRDS), one of the main causes of neonatal death, is clinically characterized by progressive dyspnea and cyanosis 1 to 2 h after birth. Corticosteroids are commonly used to prevent NRDS in clinical. However, the protective mechanism of the corticosteroids remains largely unclear.
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