Primary cultures of rat and mouse sensory neurons were used to study the entry of herpes simplex virus type 1 (HSV-1). Soluble, truncated nectin-1 but not HveA prevented viral entry. Antibodies against nectin-1 also blocked infection of rat neurons. These results indicate that nectin-1 is the primary receptor for HSV-1 infection of sensory neurons.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC149788 | PMC |
| http://dx.doi.org/10.1128/jvi.77.5.3307-3311.2003 | DOI Listing |
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