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Nodular Keratitis Associated With a Previous Diagnosis of Chronic Superficial Keratitis in a German Shepherd Dog: A First Case Report.
Vet Ophthalmol
March 2025
VetClinic, Lodz, Poland.
Objective: To describe the clinical and morphological features of a case of superficial nodular keratitis in a dog.
Case Description: A German shepherd dog previously diagnosed with chronic superficial keratitis (CSK) presented with a nonpainful, unilateral corneal nodule. After a complete ophthalmic examination, topical treatment with dexamethasone (0.
Matrical Tumors: A Comparative Molecular Analysis of Six Cases With Histological Correlations.
Am J Dermatopathol
February 2025
Unité d'Histopathologie et de Mycologie Cutanée, CHU Saint Pierre, ULB, Brussels, Belgium.
Pilomatrical tumors include pilomatricoma, melanocytic matricoma, and pilomatrical carcinoma. Similar to the normal anagen hair follicle bulb, they may be associated with benign and, rarely, with atypical pigmented dendritic melanocytes. It has been recently suggested that the term "melanocytic matricoma" be replaced with "pilomatricoma with melanocytic hyperplasia" (PMMH).
View Article and Find Full Text PDFEvaluation and Diagnosis of Longitudinal Melanonychia: A Clinical Review by a Nail Expert Group.
J Am Acad Dermatol
February 2025
Weill Cornell Medicine, Department of Dermatology, New York, NY, USA. Electronic address:
Longitudinal melanonychia (LM), a brown-black band on one or multiple nails, is commonly encountered in clinical practice. Benign LM may be due to exogenous (external, blood, bacterial, mycotic) or endogenous (melanin) pigment. Histopathologically, melanin-derived LM may result from overproduction of melanin by a normal number of melanocytes (melanocytic activation) due to physiologic, local, systemic, iatrogenic, syndromic, and drug-induced causes, or from benign (nail matrix nevus and lentigo) or malignant (nail unit melanoma [NUM]) melanocyte hyperplasia.
View Article and Find Full Text PDFTumoral Melanosis: A Case Series of a Rare Clinical Entity.
Dermatol Ther (Heidelb)
February 2025
Department of Dermatology, University of Brescia, Piazzale Spedali Civili 1, Brescia, Italy.
Tumoral melanosis (TM) is a rare entity thought to result from the complete regression of melanoma. Clinically, TM resembles malignant melanocytic lesions, presenting as hyperpigmented flat or papulonodular lesions. Histologically, TM lacks melanocytes, instead showing inflammation, fibrosis, and melanophages.
View Article and Find Full Text PDFConcurrent syringocystadenoma papilliferum and basal cell carcinoma arising from nevus sebaceous.
BMJ Case Rep
February 2025
Surgery, Yale New Haven Health System, Bridgeport, Connecticut, USA.
Here, we report a case of a female adult patient presenting with fleshy lesions on her scalp who underwent elective excision, and two separate lesions were identified on histopathology. She was found to have an unusual concurrent presentation of syringocystadenoma papilliferum (SCAP) and basal cell carcinoma, emphasising the importance of differential diagnosis in cutaneous lesions. While SCAP is benign, the presence of basal cells necessitates careful monitoring and appropriate treatment.
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