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Fascioliasis and schistosomiasis are parasitic trematodiases of public health and economic concern in humans and livestock. However, data on the distribution and risk factors for fascioliasis remain limited, while epidemiological gaps hinder schistosomiasis control in Tanzania. This One Health, cross-sectional study examined the prevalence and risk factors of schistomiasis and fascioliasis in northern Tanzania, involving 310 livestock and 317 human participants from Arusha, Kilimanjaro, and Manyara regions.
View Article and Find Full Text PDFHeterogeneous zonal impacts of climate change on a wide hyperendemic area of human and animal fascioliasis assessed within a One Health action for prevention and control.
PLoS Negl Trop Dis
January 2025
Departamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Burjassot, Valencia, Spain.
The Northern Bolivian Altiplano is the fascioliasis endemic area where the highest prevalences and intensities in humans have been recorded. In this hyperendemic area of human fascioliasis, the disease is caused only by Fasciola hepatica and transmitted by Galba truncatula, the sole lymnaeid species present in the area. When analysing the link between global warning and the recently reported geographical spread of lymnaeid populations to out-border localities, a marked heterogeneous climatic change was found throughout the endemic area.
View Article and Find Full Text PDFEvaluating the In Vitro Anthelmintic Activity of Zinc Oxide Nanoparticles (ZnO-NPs) Against the Adult Stages of Fasciola hepatica.
Vet Med Sci
January 2025
Department of Zoology, Faculty of Science, Assiut University, Assiut, Egypt.
Background: Fascioliasis represents one of the most significant parasitic and foodborne zoonotic diseases in the world. Resistance to currently deployed human and veterinary flukicides is a growing health problem. Zinc oxide nanoparticles (ZnO-NPs) have developed enormous importance in nanomedicine.
View Article and Find Full Text PDFUnraveling the microRNAs Involved in Fasciolosis: Master Regulators of the Host-Parasite Crosstalk.
Int J Mol Sci
December 2024
Departamento de Anatomía y Anatomía Patológica Comparadas y Toxicología, UIC Zoonosis y Enfermedades Emergentes (ENZOEM), Universidad de Córdoba, Campus de Rabanales, Edificio Sanidad Animal, 14071 Córdoba, Spain.
Fasciolosis is a neglected tropical disease caused by helminth parasites of the genus spp., including () and (), being a major zoonotic problem of human and animal health. Its control with antihelminthics is becoming ineffective due to the increase in parasite resistance.
View Article and Find Full Text PDFInitial Magnetic Resonance Imaging Findings in Hepatic Fascioliasis and Serological and Radiological Response After Triclabendazole Treatment.
Am J Trop Med Hyg
December 2024
Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Article Synopsis
- Fascioliasis is a disease mainly found in livestock but has seen an increase in human cases in Korea, linked to a green vegetable juice delivery service.
- Patients diagnosed with fascioliasis often presented with specific symptoms like eosinophilia and were treated with triclabendazole, showing varying recovery patterns in liver abscesses over time.
- MRI findings indicated that late-diagnosed patients had a higher incidence of bile duct issues, while antibody levels and eosinophil counts significantly declined after treatment, suggesting the need for ongoing monitoring.
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