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Double Povidone-Iodine 5% Preparation Before Cataract Surgery for Endophthalmitis Prevention.

Eye Contact Lens

January 2025

UPMC Eye Center (J.L.O., L.Z., A.M., E.G.R., R.M.Q.S., D.K.D.), University of Pittsburgh School of Medicine, Pittsburgh, PA; Charles T. Campbell Laboratory of Ophthalmic Microbiology (A.M., E.G.R., R.M.Q.S., D.K.D.), Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA; Associated Retina Consultants (J.L.O.), Phoenix, AZ; and San Antonio Eye Center (J.W.), San Antonio, TX.

Objective: To compare endophthalmitis rates after cataract extraction in patients with different preoperative prophylaxis: double povidone-iodine preparation with topical antibiotics versus a control group.

Methods: All cases of postoperative endophthalmitis over the last 17 years were reviewed. Incidence rates of endophthalmitis for all cataract surgeries (current procedural terminology codes 66982 and 66984) performed by 26 surgeons were calculated.

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Article Synopsis
  • The study aimed to compare the effectiveness of iodine compounds and levofloxacin in cleaning the conjunctival sac after cataract surgery.
  • It involved 128 patients who received either levofloxacin or diluted iodine drops for a week after surgery, with bacterial cultures taken before surgery and at one and two months post-op.
  • Results showed that both treatments reduced bacterial contamination initially, but levofloxacin was more effective in reducing bacterial DNA; however, it also led to the emergence of more resistant bacteria over time, unlike the iodine treatment.
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Article Synopsis
  • This study aimed to evaluate the effectiveness of a new ophthalmic solution made from ozonated sunflower oil in liposomes combined with hypromellose against the standard povidone iodine 5% in reducing bacterial presence in patients before eye injections.
  • The research involved 195 patients, where one eye received the new treatment (Ozodrop and BlefOX) while the other was treated with povidone iodine, with swabs taken from both eyes to measure microbial levels before and after treatment.
  • Results showed that the new treatment significantly decreased bacterial loads more than povidone iodine alone, indicating its potential as a superior antiseptic for ocular procedures.
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Pattern of Preferred Cataract Surgery Practices in Morocco: A Survey-Based Study.

Cureus

March 2024

Ophthalmology A, Hopital Des Specialités, Faculté de Médecine et de Pharmacie de Rabat, Rabat, MAR.

Aim and methodology The aim of the study was to describe the preferred cataract surgery practices among Moroccan ophthalmologists and compare them with practices in other countries. An online survey consisting of 29 multiple-choice questions was sent to Moroccan ophthalmologists. The questions were centered on the preferred cataract surgical practices of the participants.

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Objectives: the aim was to compare 2 drops of either 5% chloramphenicol, 1% povidone-iodine or 5% povidone-iodine before cataract surgery on reducing the colonisation of bacterial flora in the conjunctiva.

Design: This was a double-blind, randomised clinical trial study.

Setting: Patients referred to Shahid Sadoughi Hospital in Yazd, Iran, for cataract surgery were studied.

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