The effect of cigarette smoke on lipid peroxidation and antioxidant enzymes such as catalase, superoxide dismutase, glutathione peroxidase and on the concentration of N-methyl-d-aspartate receptor (NMDAR) subunits 2A and 2B in the hippocampus of Sprague-Dawley rats exposed to cigarette smoke for 2h/day for a period of 4 weeks was determined. It was observed that NMDAR 2A and 2B concentrations in the hippocampus were enhanced in the case of animals exposed to cigarette smoke, whereas lipid peroxidation and antioxidant enzyme activities did not show any change as compared to control animals. The results of our study suggest that cigarette smoke induces NMDAR 2A and 2B expression in the hippocampus, and that this is not due to an increased lipid peroxidation, because cigarette smoke has no effect on lipid peroxidation and antioxidant enzyme activities in the hippocampus.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/cbf.990 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Use of flavor capsule cigarettes and their preliminary impact on smoking cessation in Mexico: an exploratory study.
J Health Popul Nutr
January 2025
Department of Public Health Sciences, University of Rochester Medical Center, Saunders Research Building Crittenden Blvd, Rochester, New York, 14642, USA.
Background: No study has assessed the impact of flavor capsule cigarettes (FCCs) on smoking cessation. Thus, the purpose of this exploratory study was to assess (1) the sociodemographic and smoking-related characteristics associated with using FCCs, and (2) the preliminary impact of FCCs on smoking cessation.
Methods: This study is a secondary data analysis of a single-arm study with 100 individuals living in Mexico who smoked and received a smoking cessation mHealth intervention and pharmacotherapy support.
Genetic associations between orexin genes and phenotypes related to behavioral regulation in humans, including substance use.
Mol Psychiatry
January 2025
Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, 08854, USA.
The hypothalamic neuropeptide system of orexin (hypocretin) neurons provides projections throughout the neuraxis and has been linked to sleep regulation, feeding and motivation for salient rewards including drugs of abuse. However, relatively little has been done to examine genes associated with orexin signaling and specific behavioral phenotypes in humans. Here, we tested for association of twenty-seven genes involved in orexin signaling with behavioral phenotypes in humans.
View Article and Find Full Text PDFUsing augmented reality to deliver cue exposure treatment for smoking cessation: App usability findings and protocol for a randomized controlled trial.
Contemp Clin Trials
January 2025
Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA; Department of Psychology, University of South Florida, Tampa, FL, USA; Department of Oncological Sciences, University of South Florida, Tampa, FL, USA. Electronic address:
Background: Augmented Reality (AR) is a rapidly developing technology with potential utility for treating addictive behaviors, including tobacco smoking. AR inserts digital images into a natural real-time scene as viewed on a smartphone or other video devices. With respect to smoking cessation, AR can place virtual smoking cues (i.
View Article and Find Full Text PDFThe Promotion of Oral Nicotine Pouches for Non-Smoking Cessation Purposes on TikTok.
Nicotine Tob Res
January 2025
Faculty of Public Health & Policy, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, United Kingdom.
Article Synopsis
- This study examines the most popular TikTok videos related to ZYN oral nicotine pouches, highlighting their positive sentiment and the demographics of the creators who often portray the product humorously.
- Out of the top 100 videos analyzed, which collectively amassed over 400 million views, a significant majority (79%) presented ZYN in a favorable light, with 71% of the videos featuring the product directly.
- Only a small number of videos included disclaimers about nicotine risks, and nearly 10% of content creators had links to websites selling ONPs, indicating a commercial bias in the promotion of these products.
Electronic cigarettes for smoking cessation.
Cochrane Database Syst Rev
January 2025
Department of Health Promotion and Policy, University of Massachusetts, Amherst, MA, USA.
Background: Electronic cigarettes (ECs) are handheld electronic vaping devices that produce an aerosol by heating an e-liquid. People who smoke, healthcare providers, and regulators want to know if ECs can help people quit smoking, and if they are safe to use for this purpose. This is a review update conducted as part of a living systematic review.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!