[Frequencies distribution of GSTT1 and GSTM1 null genotypes in 24 Yunnan populations].

Zhonghua Yi Xue Yi Chuan Xue Za Zhi

Human Genetics Center, Yunnan University, Kunming, Yunnan, 650091 PR China.

Published: February 2003

Objective: To investigate the frequencies distribution of GSTT1 and GSTM1 null genotypes in 24 Yunnan populations.

Methods: GSTT1 and GSTM1 genotypes were analyzed by PCR procedure.

Results: The range of frequencies for GSTT1 and GSTM1 null genotypes in the populations were 0.188-0.633 and 0.400-0.745, respectively, and in the districts were 0.286-0.583, 0.433-0.745 respectively. There was significant relationship between GSTT1 frequencies and populations.

Conclusion: The frequencies of GSTT1 and GSTM1 null genotypes in 24 Yunnan populations were different, but they were almost the same in different districts of Yunnan.

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