From the water-soluble portion of the methanol extract of the fresh rhizome of Atractylodes japonica, five new sesquiterpenoid glycosides, including a compound having a secoguaiane skeleton, and a new aromatic compound glycoside were isolated together with ten known compounds. Their structures were clarified by spectral investigation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1248/cpb.51.152 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Research progress on extraction, separation, structure, and biological activities of polysaccharides from the genus Atractylodes: A review.
Int J Biol Macromol
December 2024
Wuya College of Innovation, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address:
Plants of the genus Atractylodes are perennial herbaceous plants in the family Asteraceae, whose rhizome is often used in the production of medicines and health products. There are 6 main species in this genus, namely A. macrocephala, A.
View Article and Find Full Text PDFTwo new guaiane-type sesquiterpene glycosides from Koidz. ex Kitam.
Nat Prod Res
October 2024
Ministry of Education, Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Harbin, China.
Article Synopsis
- * Their chemical structures were determined using advanced techniques like spectroscopy and mass spectrometry, with absolute configurations confirmed through electronic circular dichroism calculations.
- * The new compounds were tested for their ability to kill cancer cells, showing that one compound was effective against three types of cancer cells (HT-29, A-549, and MCF-7), while the other was effective against only two (HT-29 and MCF-7).
Vigeo Promotes Myotube Differentiation and Protects Dexamethasone-Induced Skeletal Muscle Atrophy via Regulating the Protein Degradation, AKT/mTOR, and AMPK/Sirt-1/PGC1α Signaling Pathway In Vitro and In Vivo.
Nutrients
August 2024
Musculoskeletal and Immune Disease Research Institute, School of Medicine, Wonkwang University, 460 Iksandae-ro, Iksan 54538, Republic of Korea.
Sarcopenia, a condition caused by an imbalance between muscle growth and loss, can severely affect the quality of life of elderly patients with metabolic, inflammatory, and cancer diseases. Vigeo, a nuruk-fermented extract of three plants ( Maxim (ESM), (Miq.) Nakai (AJN), and Koidzumi (AJK)) has been reported to have anti-osteoporotic effects.
View Article and Find Full Text PDFCKD-497 inhibits NF-kB signaling and ameliorates inflammation and pulmonary fibrosis in ovalbumin-induced asthma and particulate matter-induced airway inflammatory diseases.
Front Pharmacol
August 2024
Department of Synthetic Chemistry, Chong Kun Dang Research Institute, Yongin-si, Gyeonggi-do, Republic of Korea.
Air pollution, allergens, and bacterial infections are major contributors to pathological respiratory disorders worldwide. CKD-497, derived from the rhizome of and the fruits of , is known for its ability to relieve cough and facilitate phlegm expectoration. However, its protective action against allergic asthma and fine dust-induced lung inflammation, along with its underlying mechanisms, have not been thoroughly investigated.
View Article and Find Full Text PDFIsovaleryl Sucrose Esters from and Their Cytotoxic Activity.
Molecules
June 2024
Key Laboratory of Basic and Application Research of Beiyao, Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Cancer represents one of the most significant health challenges currently facing humanity, and plant-derived antitumour drugs represent a prominent class of anticancer medications in clinical practice. Isovaleryl sucrose esters, which are natural constituents, have been identified as having potential antitumour effects. However, the mechanism of action remains unclear.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!