AI Article Synopsis
- The study aimed to explore how 89Strontium (89Sr) radiation therapy affects immune function in patients with multiple bone metastases.
- Researchers measured T cell subsets, Natural Killer (NK) cell activity, and lymphocyte transformation rates (LTR) before and after treatment.
- Results showed that after treatment, patients experienced less pain and exhibited improved immune function, while those with persistent pain did not show significant immune changes.
Article Abstract
Objective: To investigate the influence of 89Sr on the cell immune function in patients with multiple bone metastases.
Methods: Patients with multiple bone metastases were treated with in vivo radiation of 89Sr. The T cell subsets, NK cell activities, and lymphocyte transformation rate (LTR) of multiple bone metastases before and after the 89Sr treatment were measured.
Results: With the palliation of the pain of the patients after the 89Sr treatment, the T cell subset level, NK cell activities, and LTR increased. There was no significant change in the patients with the pain.
Conclusion: Treating multiple bone metastases with 89Sr can improve the cell immune function of the patients to a certain extent.
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