[Clinical curative effect of dengzhanhua injection on acute cerebral infarction: a report of 100 cases].

Hunan Yi Ke Da Xue Xue Bao

Department of Traditional Chinese Medicine, Second Xiangya Hospital, Central South University, Changsha 410011, China.

Published: June 2002

Objective: To observe the clinical curative effect of dengzhanhua injection on acute cerebral infarction.

Methods: One hundred cases of acute cerebral infarction were treated with dengzhanhua injection (Group A) and 62 treated with fufangdanshen injection (Group B). The curative effects and the patients' hemorrheology and lipemia before and after the treatment were compared.

Results: The total effective rate and evidently effective rate of Group A were significantly higher than those of Group B (92.0% vs. 75.8%, 44.0 vs. 29.0%, P < 0.01). The levels of hemorrheology and lipemia in 72 hyperviscosityemia patients and 76 hyperlipidemia patients in Group A were significantly improved after the treatment. The integral difference of nerve function injury and the obsorbed situation of infarct focus in Group A were significantly higher than those in Group B. Group A had no adverse reaction during the treatment.

Conclusion: Dengzhanhua injection in the treatment of acute cerebral infarction is safe and effective.

Download full-text PDF

Source

Publication Analysis

Top Keywords

dengzhanhua injection
16
acute cerebral
16
cerebral infarction
12
curative dengzhanhua
8
injection acute
8
group
8
injection group
8
hemorrheology lipemia
8
effective rate
8
group higher
8

Similar Publications

Purpose: To investigate the protective effect of breviscapine on myocardial ischemia-reperfusion injury (MIRI) in diabetes rats.

Methods: Forty rats were divided into control, diabetes, MIRI of diabetes, and treatment groups. The MIRI of diabetes model was established in the latter two groups.

View Article and Find Full Text PDF

This study aims to systematically review the efficacy and safety of different traditional Chinese medicine injections combined with conventional treatment for patients with post-acute myocardial infarction heart failure. The relevant randomized controlled trial(RCT) was retrieved from CNKI, Wanfang, VIP, SinoMed, PubMed, EMbase, and Cochrane Library with the time interval from inception to May 13, 2023. Two reviewers independently screened the literature, extracted data, and assessed the risk of bias of the included studies.

View Article and Find Full Text PDF
Article Synopsis
  • Erigeron breviscapus is a traditional medicine used by several ethnic minorities in China for treating ailments, including ischemic stroke, although its mechanisms are not fully understood.
  • This study employs advanced metabonomics techniques to understand how Erigeron breviscapus injection impacts a rat model of ischemic stroke and its interactions with mitochondrial apoptosis pathways.
  • Results indicate that the injection significantly reduces cerebral infarction size and improves tissue health, as evidenced by an increase in Nissl bodies in the treated rats.
View Article and Find Full Text PDF

Objectives: To study the protective effect of breviscapine against brain injury induced by intrauterine inflammation in preterm rats and its mechanism.

Methods: A preterm rat model of brain injury caused by intrauterine inflammation was prepared by intraperitoneal injections of lipopolysaccharide in pregnant rats. The pregnant rats and preterm rats were respectively randomly divided into 5 groups: control, model, low-dose breviscapine (45 mg/kg), high-dose breviscapine (90 mg/kg), and high-dose breviscapine (90 mg/kg)+ML385 [a nuclear factor erythroid 2-related factor 2 (Nrf2) inhibitor, 30 mg/kg] (=10 each).

View Article and Find Full Text PDF

Podocyte injury is a critical factor in the pathogenesis of diabeticnephropathy (DN). Emerging evidence has demonstrated that breviscapine (Bre) exerts a renoprotective effect on diabetic rats. However, the effects of Bre on regulating podocyte injury under high glucose (HG) conditions remain unclear.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!