[The apoptosis of human gastric cancer cell induced by Acanthopanax giraldii Harms var Hispidus Hoo Polysaccharides in vitro].

Hua Xi Yi Ke Da Xue Xue Bao

Department of Nutrition and Food Hygiene, West China School of Public Health, Sichuan University, Chengdu 610041, China.

Published: April 2002

Objective: To investigate the effect of Acanthopanax Giraldii Harms Var Hispidus Hoo polysaccharides (AGP-I) on the human gastric cancer cell.

Methods: DNA agarose gel electrophoresis and flow cytometry techniques were adopted.

Results: After treatment with AGP-I, apoptotic peaks in cell cycle analysis and DNA ladder on the agarose gel were observed.

Conclusion: The results indicate that AGP-1 may inhibit cancer by inducing cancer cell apoptosis.

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