Investigated the relation between memory specificity and self-reported trauma, depressive symptoms, and other emotional characteristics in a group of adolescent inpatients. Research with adults has shown that clinical depression is associated with a difficulty in retrieving specific autobiographical memories in response to cue words, and this pattern of overgeneral memory is related to the prognosis of depression. Research has also shown a clear positive association between self-reported trauma and overgeneral memory. This study's results showed that higher levels of trauma--both in terms of total number and in terms of severity or related distress--were associated with reduced autobiographical memory specificity (AM). None of the other emotional variables, such as depression, anxiety, worry, hopelessness, or subjective stress, were significantly related to the retrieval of specific memories. The results are reconcilable with Williams' (1996) developmental idea that a pattern of overgeneral AM retrieval originates in childhood trauma as a way of regulating affect.
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http://dx.doi.org/10.1207/S15374424JCCP3201_03 | DOI Listing |
Viruses
December 2024
School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.
: During the acute phase of COVID-19, a number of immunological abnormalities have been reported, but few studies longitudinally analyzed the specific subsets of peripheral blood lymphocytes. : In this observational, prospective, and longitudinal study, adult patients developing acute pneumonia during the COVID-19 pandemic have been followed up for 12 months. Peripheral blood lymphocyte subsets were assessed (with a specific focus on the memory markers) at 6 time points after the disease onset until 12 months.
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December 2024
Department of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan, TX 77807, USA.
In this study, we revealed a critical role of eukaryotic elongation factor-2 kinase (eEF-2K), a negative regulator of protein synthesis, in regulating T cells during vaccinia virus (VACV) infection. We found that eEF-2K-deficient (eEF-2K⁻/⁻) mice exhibited a significantly higher proportion of VACV-specific effector CD8 T cells without compromising the development of VACV-specific memory CD8 T cells. RNA sequencing demonstrated that eEF-2K⁻/⁻ VACV-specific effector CD8 T cells had enhanced functionality, which improves their capacity to combat viral infection during the effector phase.
View Article and Find Full Text PDFNutrients
January 2025
Neuroepidemiology Department, The Cyprus Institute of Neurology and Genetics, Nicosia 2371, Cyprus.
Background/objectives: Dementia is not a single disease but an umbrella term that encompasses a range of symptoms, such as memory loss and cognitive impairments, which are severe enough to disrupt daily life. One of the most common forms of dementia is Alzheimer's Disease (AD), a complex neurodegenerative condition influenced by both genetic and environmental factors. Recent research has highlighted diet as a potential modifiable risk factor for AD.
View Article and Find Full Text PDFPolymers (Basel)
January 2025
School of Polymer Engineering, Institute of Engineering, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Poly(lactic acid) (PLA) exhibits excellent shape memory properties but suffers from brittleness and a high glass transition temperature (T), limiting its utility in flexible and durable applications. This study explored the modification of PLA properties through the incorporation of poly(ethylene glycol) (PEG), varying in both content (5-20 wt%) and molecular weight (4000-12,000 g/mol), to enhance its suitability for specific applications, such as medical splints. The PLA/PEG blend, containing 15 wt% PEG and with a molecular weight of 12,000 g/mol, exhibited superior shape fixity (99.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Department of Electrical Engineering, Faculty of Engineering, Universitas Indonesia, Depok 16424, Indonesia.
The Internet of Things (IoT) has emerged as a crucial element in everyday life. The IoT environment is currently facing significant security concerns due to the numerous problems related to its architecture and supporting technology. In order to guarantee the complete security of the IoT, it is important to deal with these challenges.
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