AI Article Synopsis
- The study explored the relationship between Mycobacterium tuberculosis infection and allergic reactions (atopy) in 252 asthmatic children.
- In the research, tuberculin tests were used to identify tuberculosis infection, and skin prick tests assessed allergic sensitivities to common allergens.
- The results showed no significant difference in atopy rates between children with and without tuberculosis infection, indicating that tuberculosis reactivity does not correlate inversely with atopy in this group.
Article Abstract
Background: It has been postulated that there is an inverse association between mycobacterium tuberculosis infection and atopy. We aimed to investigate if there is a similar relation in our study group, consisting 252 asthmatic children.
Methods: In tuberculin testing indurations greater than or equal to 5 mm were accepted as positive. The most common aeroallergens were used in skin prick testing and reactions > or = 3 mm were accepted as positive.
Results: In 139 patients PPD was negative, where as in 113 patients PPD was positive. Among the PPD (-) patients skin prick test was positive in 64 % (n = 89). Among the PPD (+) patients skin prick test was positive in 71 % (n = 80). As the two groups were compared for having positive skin prick test reactions no statistically significant difference was detected between them (p = 0.283).
Conclusions: Tuberculin reactivity is not inversely associated with atopy in asthmatic children.
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| http://dx.doi.org/10.1016/s0301-0546(03)79159-9 | DOI Listing |
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