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Evaluation of Cytotoxic Activity of Cell Biomass from and on Melanoma Cancer Cell.
Molecules
October 2024
Laboratory of Pharmaceutical Biology and Biotechnology, Department and Division of Practical Cosmetology and Skin Diseases Prophylaxis, Poznan University of Medical Sciences, Collegium Pharmaceuticum, 3 Rokietnicka St., 60-806 Poznan, Poland.
Article Synopsis
- - Melanoma, a type of skin cancer, is becoming more common, and there is interest in using plant-based products that have low toxicity as potential treatments.
- - The study focused on inducing callus biomass from specific plants using growth regulators and creating methanolic extracts to test their effects on human melanoma (MeWo) cells and human fibroblast cells (MRC-5).
- - The results showed that certain extracts and fractions had significant cytotoxic effects on melanoma cells, indicating their potential for use in cancer treatment, especially the extracts with higher concentrations of methanol.
Saponin Fractions from L. Induce Apoptosis in Ovarian SKOV-3 Cancer Cells.
Plants (Basel)
June 2023
Laboratory of Pharmaceutical Biology and Biotechnology, Department and Division of Practical Cosmetology and Skin Diseases Prophylaxis, Poznan University of Medical Sciences, Collegium Pharmaceuticum, 3 Rokietnicka St., 60-806 Poznan, Poland.
(1) The cytotoxicity and antioxidant activity of different fractions as well as the pro-apoptotic activity of saponin fractions from L. in SKOV-3 was investigated. (2) In screening studies, the cytotoxicity of six fractions on SKOV-3 was examined by LDH and SRB assays.
View Article and Find Full Text PDFPhytochemical Diversity Comparison in Leaves and Roots of Wild and Micropropagated Latvian Sea Holly ( L.).
Molecules
May 2023
Institute for Environmental Solutions, "Lidlauks", Priekuli Parish, LV-4126 Cesis, Latvia.
The goal of the current study was to compare the chemical composition of the roots, shoots, and leaves of wild-growing L., and of in vitro and in field-cultivated plants in Latvia. The essential oil yield obtained by hydrodistillation ranged from 0.
View Article and Find Full Text PDFEryngium caeruleum: an update on ethnobotany, phytochemistry and biomedical applications.
Chin Med
September 2022
Department of Toxicology, University of Medicine and Pharmacy of Craiova, 200349, Craiova, Romania.
Background: A biennial or perennial plant of the Apiaceae family, Eryngium caeruleum M. Bieb. is traditionally used in medicine as an antitoxic, diuretic, digestive, anti-inflammatory and analgesic drug.
View Article and Find Full Text PDFSpecies as a Potential Ally for Treating Metabolic Syndrome and Diabetes.
Front Nutr
May 2022
Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias, Monterrey, Mexico.
Medicinal plants possess natural compounds that can be used as an alternative for synthetic medicines that may cause long-term side effects on patients such as neurocognitive effects, muscular and hepatic toxicity. Metabolic Syndrome is associated with increased risk of several diseases such as diabetes, cardiovascular disease, dyslipidemia, and hypertension thus, becoming the greatest challenge as a growing public health concern worldwide. Latin-American countries possess a wide diversity of medicinal plants that have been used to treat different health conditions since pre-Hispanic times.
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