Article is devoted to some new aspects of biomedical support and countermeasures during a manned Mars mission. Significant differences in crew--Mission control interaction in a Martian and orbital flight are described. Special attention is paid to the problem of the Martian crew autonomy and decision-making. The authors give some practical recommendations for improvement of the space flight medical support system existing in Russia to meet the needs of a Martian expedition.
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Exp Physiol
January 2025
Department of Biology, Mount Royal University, Calgary, AB, Canada.
Cerebrovascular regulation is critically dependent upon the arterial partial pressure of carbon dioxide ( ), owing to its effect on cerebral blood flow, tissue , tissue proton concentration, cerebral metabolism and cognitive and neuronal function. In normal environments and in the absence of pathology, at least over acute time frames, hypercapnia is usually managed readily via the respiratory chemoreflex arcs and/or acid-base buffering capacity, such that there is minimal impact on cerebrovascular and neurological function. However, in non-normal environments, such as enclosed spaces, or with pathology, extended exposures to elevations in can be detrimental to cerebral health.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Electrical, Computer, and Biomedical Engineering, Toronto Metropolitan University, Toronto, ON M5B 2K3, Canada.
Autonomous technologies have revolutionized transportation, military operations, and space exploration, necessitating precise localization in environments where traditional GPS-based systems are unreliable or unavailable. While widespread for outdoor localization, GPS systems face limitations in obstructed environments such as dense urban areas, forests, and indoor spaces. Moreover, GPS reliance introduces vulnerabilities to signal disruptions, which can lead to significant operational failures.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Division of Space, Ecological, Arctic, and Resource-limited (SPEAR) Medicine, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA 02114.
One of the most surprising and important findings of the first human landings on the Moon was the discovery of a very fine layer of lunar dust covering the entire surface of Moon along with the negative impacts of this dust on the well-being and operational effectiveness of the astronauts, their equipment, and instrumentation. The United States is now planning for human missions to Mars, a planet where dust can also be expected to be ubiquitous for many or most landing sites. For these missions, the design and operations of key hardware systems must take this dust into account, especially when related to crew health and safety.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Division of Earth and Planetary Sciences, California Institute of Technology, Pasadena, CA 91125.
Mars Sample Return (MSR) has been the highest flagship mission priority in the last two Planetary Decadal Surveys of the National Academies of Science, Engineering, and Medicine (hereafter, "the National Academies") and was the highest priority flagship for Mars in the Decadal Survey that preceded them. This inspirational and challenging campaign, like the Apollo program's returned lunar samples, will potentially revolutionize our understanding of Mars and help inform how other planets are explored. MSR's technological advances will keep the NASA and European Space Agency at the forefront of planetary exploration, and data on returned samples will fill knowledge gaps for future human exploration.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Center for Marine Environmental Sciences, University of Bremen, 28359 Bremen, Germany.
The search for evidence of past prebiotic or biotic activity on Mars will be enhanced by the return of samples to Earth laboratories. While impressive analytical feats have been accomplished by in situ missions on the red planet, accessing the capabilities of Earth's global laboratories will present a step change in data acquisition. Highly diagnostic markers of past life are biomarkers, organic molecules whose architecture can be attributed to once living organisms.
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