Effects of externally imposed and self-generated poloidal flows on turbulent transport in the edge region of a tokamak are investigated using 3D nonlinear global simulations of resistive pressure-gradient-driven turbulence. Transport reduction is found to be due to synergetic changes in the fluctuation amplitude and in the dephasing of the fluctuations. A scaling of the fluctuation level and turbulent diffusivity with E x B flow shear strength is deduced from these simulations. These scalings agree with recent experimental observations on edge biasing as well as with analytical models.
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http://dx.doi.org/10.1103/PhysRevLett.90.015002 | DOI Listing |
Front Immunol
January 2025
Department of Bioengineering, College of Engineering, University of Toledo, Toledo, OH, United States.
Resolution of inflammation is essential for normal tissue healing and regeneration, with macrophages playing a key role in regulating this process through phenotypic changes from a pro-inflammatory to an anti-inflammatory state. Pharmacological and mechanical (mechanotherapy) techniques can be employed to polarize macrophages toward an anti-inflammatory phenotype, thereby diminishing inflammation. One clinically relevant pharmacological approach is the inhibition of Transient Receptor Potential Vanilloid 4 (TRPV4).
View Article and Find Full Text PDFJ Phys Chem B
January 2025
Chemical Sciences Department, Homi Bhabha National Institute, Mumbai 400094, India.
This study delves into the interplay of temperature, composition, tortuosity, and electrostatic interactions on ion diffusion within cation exchange membranes. It explores the temperature dependence (16-60 °C) of the self-diffusion coefficients (SDCs) of Ba and Eu ions within the Nafion 117 cation exchange membrane, particularly in the presence of Na ions. Radiotracer techniques and electrochemical impedance spectroscopy were employed to investigate these SDCs.
View Article and Find Full Text PDFSci Rep
January 2025
School of petroleum engineering, Yangtze University, Wuhan, 430100, China.
Given the suboptimal physical properties and distinctive geological conditions of deep coalbed methane reservoirs, any reservoir damage that occurs becomes irreversible. Consequently, the protection of these deep coalbed methane reservoirs is of paramount importance. This study employs experimental techniques such as scanning electron microscopy, X-ray diffraction, and micro-CT imaging to conduct a comprehensive analysis of the pore structure, mineral composition, fluid characteristics, and wettability of coal seams 3# and 15# in the northern Qinshui Basin of China.
View Article and Find Full Text PDFSci Rep
January 2025
Qatar Environment & Energy Research institute (QEERI), Hamad Bin Khalifa University (HBKU), Qatar Foundation, P.O. Box 34110, Doha, Qatar.
Keto-enol tautomerism in organic molecules presents a potential for modulating the charge transport at the nanoscale. The reduction of the isomerization barrier and favoring the highly conductive enol form are the main challenges towards practical implementation of this phenomenon. Using density functional theory calculations, we have demonstrated that pyridinic nitrogen in biphenyl molecules with keto-enol tautomerism can successfully make the conductive enol form energetically more favorable.
View Article and Find Full Text PDFBone Res
January 2025
Department of Endodontology, School of Dental Medicine, University of Connecticut Health, Farmington, CT, USA.
Craniometaphyseal dysplasia (CMD), a rare craniotubular disorder, occurs in an autosomal dominant (AD) or autosomal recessive (AR) form. CMD is characterized by hyperostosis of craniofacial bones and metaphyseal flaring of long bones. Many patients with CMD suffer from neurological symptoms.
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