Risk factors for hypoandrogenemia among low-weight, human immunodeficiency virus (HIV)-infected patients are not known. Testosterone levels of 69 HIV-infected women with low weight and weight loss were compared with levels for 25 healthy, age- and body mass index-matched control subjects. HIV-infected subjects were of low weight, with a mean (+/- standard deviation) weight loss of -17.6% +/- 9.7% from preillness maximum, and 42% of HIV-infected subjects had a body mass index of <20 kg/m(2). Forty-nine percent of the HIV-infected population versus 8% of the control population exhibited low free testosterone levels (P<.001). Among HIV-infected women, when we controlled for chronic hepatitis status, age, and time of blood sampling, weight loss of >10% of maximum weight was a significant predictor of low free testosterone levels. Free testosterone levels did not differ by drug class or antiretroviral regimen. In conclusion, decreased androgen levels are common among HIV-infected women reporting significant weight loss, independent of exposure to antiretroviral medications.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1086/367642 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Efficacy of a Community- and Family-Based Intervention on Cardiovascular Fitness and Cardiometabolic Disease Risk Factors Among Primarily Latino Families.
Am J Health Promot
January 2025
San Diego State University, School of Public Health, San Diego, CA, USA.
Background: Targeting cardiovascular fitness (CVF), rather than weight loss, may be a more acceptable and feasible outcome among Latinos.
Purpose: The purpose of this study was to test the short-term efficacy of (AFL), a fitness- and lifestyle-focused behavioral intervention to improve CVF and performance among Latino families.
Methods: Latino parent-child dyads (n = 137) were randomized to either AFL program or a waitlist control condition.
Received and Desired Support Needs of Postoperative Bariatric Surgery Patients.
Gastroenterol Nurs
January 2025
About the authors: Katherine K. Sink, PhD, APRN-CNS, is a Retired Professor, University of Toledo, Toledo, Ohio.
Obesity is a worldwide health concern with one highly effective solution being bariatric surgery. The purpose of this descriptive study was to explore the experiences of postoperative bariatric surgery patients related to perceptions of helpful interventions for achieving and maintaining weight loss. Fifteen participants shared their perceived support received and their perceptions of desired support needed after bariatric surgery.
View Article and Find Full Text PDFDiscussion: Postbariatric Panniculectomy: Postoperative Complications by Weight Loss Surgery Type.
Plast Reconstr Surg
February 2025
From the Department of Plastic Surgery, University of Pittsburgh Medical Center.
Integrin Trafficking, Fibronectin Architecture, and Glomerular Injury upon AdipoR1 Depletion.
J Am Soc Nephrol
January 2025
Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Background: Deficiency of adiponectin and its downstream signaling may contribute to the pathogenesis of kidney injury in type 2 diabetes. Adiponectin activates intracellular signaling via adiponectin receptors 1 and 2 (AdipoR1 and AdipoR2), but the role of AdipoR-mediated signaling in glomerular injury in type 2 diabetes remains unknown.
Methods: The expression of AdipoR1 in the kidneys of people with type 2 diabetes and the expression of podocyte proteins or injury markers in the kidneys of AdipoR1-knockout (AdipoR1-KO) mice and immortalized AdipoR1-deficient human podocytes were investigated by immunohistochemistry and immunoblotting.
Severe Deficiency of Vitamin D and Anthracycline-Taxane Regimen are associated with Cachexia Following Breast Cancer Chemotherapy: A Single Center Assessment Using Two Consensus-Based Criteria.
Asian Pac J Cancer Prev
January 2025
Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito General Hospital Yogyakarta, Indonesia.
Background: Cancer cachexia in breast cancer (BC) patients is not commonly reported, particularly in Indonesia. This study assessed the prevalence of cachexia in local patients with BC receiving chemotherapy, and the associated factors.
Methods: This cross-sectional study included 160 BC patients who started chemotherapy between July 2018 and June 2022.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!