Efficient ring-opening reaction of epoxides and aziridines promoted by tributylphosphine in water.

J Org Chem

Shanghai-Hong Kong Joint Laboratory in Chemical Synthesis, State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China.

Published: February 2003

Tributylphosphine was found to be an effective promoting reagent for the ring-opening reaction of various epoxides and aziridines with nucleophile to produce corresponding anti-bifunctional products in moderate to excellent yields in water.

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Source
http://dx.doi.org/10.1021/jo025983sDOI Listing

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