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Adolescent and Young Adults with Gastric Cancer (AYA-GC)-The Dilemma of an Under-Represented Group: A Multi-Institutional Analysis from the Indian Subcontinent.
South Asian J Cancer
April 2024
Department of Medical Oncology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Soumya Surath PandaGastric cancer (GC) is often ignored at a young age, which frequently leads to tragic consequences. The worldwide incidence of GC is increasing at a young age. In view of the limited Indian publication, we sought to characterize clinicopathological parameters and risk factors in the adolescents and young adults (AYA) population.
View Article and Find Full Text PDFGenomic Landscape of Adenocarcinomas Across the Gastroesophageal Junction: Moving on from the Siewert Classification.
Ann Surg
June 2024
Thoracic Service, Department of Surgery, MSK.
Article Synopsis
- The study aims to analyze the relationship between the Siewert classification of gastroesophageal junction adenocarcinomas and their genomic profiles to better inform staging and treatment decisions.
- The research included 350 patients and found that Siewert type I and II tumors displayed similar genomic features to lower esophageal tumors, while Siewert type III tumors had distinct characteristics more aligned with gastric cancers.
- The findings suggest that molecular classification may be more beneficial than traditional anatomical classification for guiding treatment and improving prognosis in these cancer cases.
Supradiaphragmatic Jejunal Perforation Following Total Gastrectomy With Esophagojejunostomy Reconstruction for Gastric Adenocarcinoma.
Cureus
April 2024
Department of Surgery, King Faisal Specialist Hospital and Research Centre, Riyadh, SAU.
Nasogastric tube decompression is a common technique used after abdominal surgery as it is widely accepted to play a role in the management of postoperative ileus and possibly reduce anastomotic leaks after gastrointestinal surgery. However, the routine practice of nasogastric/nasoenteric tube decompression in elective abdominal surgeries has been challenged due to the increased incidence of pulmonary complications and the argued lack of expected benefit. Here, we present a rare complication of nasogastric tube drainage following a routine total gastrectomy for signet-ring cell adenocarcinoma of the cardia in a 43-year-old female.
View Article and Find Full Text PDF[A Case of Stage Ⅳ Gastric Cancer with Multiple Liver Metastases, Resected Primary Tumor after Chemotherapy, and Alive for 3.5 Years without Recurrence].
Gan To Kagaku Ryoho
April 2024
Dept. of Surgery, Onomichi General Hospital.
A 67-year-old man visited our hospital for epigastric pain. Esophagogastroduodenoscopy(EGD)revealed type 2 gastric cancer from the cardia to the gastric angle, and histopathological examination revealed papillary adenocarcinoma(pap), HER2-positive. Contrast-enhanced CT showed wall thickening mainly in the posterior wall of the gastric body, enlarged lymph nodes that were lumped together with the main lesion, and 8 low-absorption areas with ring shaped contrast effects in both lobes of the liver.
View Article and Find Full Text PDFClinicopathological and endoscopic features of Helicobacter pylori infection-negative gastric cancer in Japan: a retrospective study.
Clin Endosc
July 2024
Department of Pathology, Fukuoka University Chikushi Hospital, Fukuoka, Japan.
Background/aims: Helicobacter pylori infection-negative gastric cancer (HPNGC) has not been systematically investigated in consecutive patients. Hence, this study aimed to investigate the clinicopathological and endoscopic features of HPNGC.
Methods: This single-center retrospective study selected participants from patients with gastric cancer who were treated at the Fukuoka University Chikushi Hospital between January 2013 and December 2021.
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