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High temperature QDs organization and re-crystallization in glass supported MgO QDs doped PMMA film.
Sci Rep
January 2025
Condensed Matter Physics & Nanoscience Research Laboratory, Department of Physics and Material Science, Madan Mohan Malaviya University of Technology, Gorakhpur, 273010, U.P, India.
Article Synopsis
- The study focuses on creating composite films of poly (methylmethacrylate) (PMMA) blended with magnesium oxide quantum dots (MgO QDs) at varying concentrations, and the films were annealed at 130°C for different durations to observe changes in their properties.
- Analysis revealed that the initial crystallinity of the PMMA films decreased with annealing but slightly improved with the diffusion and coalescence of MgO QDs, leading to the formation of larger clusters that influenced the films' structural properties.
- The research highlights the significance of temperature and molecular forces in the evolution of the film's morphology and stability, demonstrating unique energy dissipation mechanisms and the complex interplay of inter- and intra
[Medication Reconciliation in Primary Care: Practices, Knowledge and Attitudes in the Lisbon and Tagus Valley Health Region].
Acta Med Port
January 2025
Laboratório de Farmacologia Clínica e Terapêutica. Faculdade de Medicina. Universidade de Lisboa. Lisboa; Instituto de Medicina Molecular João Lobo Antunes. Lisboa. Portugal.
Introduction: Despite the importance of medication reconciliation for the continuity of care, there is currently no information on the practices, knowledge, and attitudes of Portuguese family doctors on this subject. This study aimed to characterize the formal medication reconciliation procedures in the Lisbon and Tagus Valley Health Region, as well as the perception of family doctors in this region about what they know, how they think and how they practice medication reconciliation.
Methods: We conducted an observational, cross-sectional and descriptive study, using two observation units: primary health care units (study 1) and family doctors (study 2) in the Lisbon and Tagus Valley Health Region.
Ancient evolutionary origins of hepatitis E virus in rodents.
Proc Natl Acad Sci U S A
December 2024
Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin 10117, Germany.
Hepatitis E virus (HEV; family ) infections cause >40,000 human deaths annually. Zoonotic infections predominantly originate from ungulates and occasionally from rats, highlighting the zoonotic potential of rodent-associated hepeviruses. We conducted host genomic data mining and uncovered two genetically divergent rodent-associated hepeviruses, and two bat-associated hepeviruses genetically related to known bat-associated strains.
View Article and Find Full Text PDFThe Evolution of Extreme Genetic Variability in a Parasite-Resistance Complex.
Genome Biol Evol
October 2024
Department of Environmental Sciences, Zoology, University of Basel, Basel 4051, Switzerland.
Article Synopsis
- Genomic regions involved in parasite defense, like the MHC, are highly variable, with multiple factors like single nucleotide polymorphisms and copy number variations contributing to this diversity.
- The study focuses on the Pasteuria Resistance Complex (PRC) in the crustacean Daphnia magna, revealing significant genetic variation and non-homologous haplotypes, suggesting the region is under balancing selection and has a long evolutionary history.
- The research highlights the interplay of ancient resistance mechanisms and hyper-divergent genomic environments, offering insights into the evolution of disease resistance not just in Daphnia, but across the broader Cladocera class.
The very early evolution of biological complexity.
Trends Genet
November 2024
Department of Earth, Atmospheric and Planetary Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address:
All extant life is descended from a common ancestor, which, despite being very ancient, appears to have been a complex cellular organism. A new study by Moody et al. shows that this ancestor was not only a complex cell, but also lived within a microbial ecology likely inhabited by other complex cells.
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