Traditionally, contour interaction has been investigated at the visual acuity limit using a Landolt C and flanking bars, performance being quantified in terms of a percent correct measure. More recently, it has been shown that the properties of the contour interaction are different when larger stimuli are used: Contour interaction is not polarity specific, and spatial frequency tuning for an unflanked C is broader. Here we quantify contour interaction for stimuli 5x larger than the resolution limit in terms of contrast thresholds. We show that polarity of bars has little effect on unfiltered stimuli but does show very different effects on the spatial-frequency-tuning curves for discrimination of the Landolt C. This explains the polarity dependence of crowding at the visual acuity limit and its independence for larger unfiltered targets. Thus the underlying filtering function is composed of more than one mechanism, affected differently depending on the relative polarity of the test and flank contours.
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http://dx.doi.org/10.1364/josaa.20.000011 | DOI Listing |
J Thromb Haemost
January 2025
Department of Pathology and Laboratory Medicine; Institute of Reproductive Medicine and Developmental Sciences, The University of Kansas Medical Center, Kansas City, KS 66160. Electronic address:
Background: A loss-of-functional mutation (W1183R) in human complement factor H (CFH) is associated with complement-associated hemolytic uremic syndrome; mice carrying a similar mutation (W1206R) in CFH also develop thrombotic microangiopathy but its plasma von Willebrand factor (VWF) multimer sizes were dramatically reduced. The mechanism underlying such a dramatic change in plasma VWF multimer distribution in these mice is not fully understood.
Objective And Methods: To determine the VWF and CFH interaction and how CFH proteins affect VWF multimer distribution, we employed recombinant protein expression, purification, and various biochemical and biophysical tools.
Sci Rep
December 2024
Department of Mathematics and Statistics, College of Science, Taif University, 11099, 21944, Taif, Saudi Arabia.
In this work, we use the ansatz transformation functions to investigate different analytical rational solutions by symbolic computation. For the (2+1)-dimensional Calogero-Bogoyavlenskii Schiff (CBS) model, we derive a variety of rational solutions, such as homoclinic breather solutions (HBs), M-shaped rational solutions (MSRs), periodic cross-rationals (PCRs), multi-wave solutions (MWs), and kink cross-rational solutions (KCRs). Their dynamic is shown in figures by selecting appropriate values for the pertinent parameters.
View Article and Find Full Text PDFJ Speech Lang Hear Res
December 2024
University of California, San Francisco.
Purpose: We investigate the extent to which automated audiovisual metrics extracted during an affect production task show statistically significant differences between a cohort of children diagnosed with autism spectrum disorder (ASD) and typically developing controls.
Method: Forty children with ASD and 21 neurotypical controls interacted with a multimodal conversational platform with a virtual agent, Tina, who guided them through tasks prompting facial and vocal communication of four emotions-happy, angry, sad, and afraid-under conditions of high and low verbal and social cognitive task demands.
Results: Individuals with ASD exhibited greater standard deviation of the fundamental frequency of the voice with the minima and maxima of the pitch contour occurring at an earlier time point as compared to controls.
Nano Lett
January 2025
Department of Electrical Engineering, Ginzton Laboratory, Stanford University, Stanford, California 94305, United States.
Heterostructures composed of graphene and molybdenum trioxide (MoO) can support in-plane hybrid polaritons in the infrared. The isofrequency contour for these subwavelength polaritons can exhibit a quasi-flat region when the topological transition occurs as the doping level of graphene is tuned. Such a topological transition can be useful for optical sensing and imaging at nanoscale.
View Article and Find Full Text PDFBiomed Phys Eng Express
December 2024
Key Laboratory of Digital Medical Engineering of Hebei Province, Baoding 071000, People's Republic of China.
Malignant thyroid nodules are closely linked to cancer, making the precise classification of thyroid nodules into benign and malignant categories highly significant. However, the subtle differences in contour between benign and malignant thyroid nodules, combined with the texture features obscured by the inherent noise in ultrasound images, often result in low classification accuracy in most models. To address this, we propose a Bidirectional Interaction Directional Variance Attention Model based on Increased-Transformer, named IFormer-DVNet.
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