Methods currently exist for the precise measurement of local three-dimensional myocardial motion noninvasivly with magnetic resonace imaging tagging. From these motion estimates, strain images representing the local deformation of the myocardium can be formed to show local myocardial contraction. These images clearly show the sequence of mechanical events during the activation and relaxation of the heart, making them ideal to visualize abnormalities caused by asynchronous electrical activation or ischemia. Coupled with the near simultaneous mapping of electrical depolarization with a sock electrode array, we can investigate the relationship between electical activity and mechanical function on a local level in the in vivo heart. Registered fiber angle maps can be also be obtained in the same heart with diffusion magnetic resonance imaging to assist in the construction of the electromechanical model of the whole heart.
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http://dx.doi.org/10.1054/jelc.2002.37156 | DOI Listing |
J Hazard Mater
January 2025
School of Civil and Transportation Engineering, Guangdong University of Technology, Guangzhou 510006, PR China. Electronic address:
Groundwater is widely threatened by hazardous manganese and ammonia. In present study, a novel gravity-driven fixed-bed ceramic membrane filtration (GDFBCM) with critical PAC-MnOx-ceramsite filters was built to address these issues. Static ceramsite filters in GDCM significantly increased membrane flux from 11 L/m·h to 18 L/m·h on the 50th day of filtration.
View Article and Find Full Text PDFCell Discov
January 2025
Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
A well-balanced ion channel trafficking machinery is paramount for the normal electromechanical function of the heart. Ion channel variants and many drugs can alter the cardiac action potential and lead to arrhythmias by interfering with mechanisms like ion channel synthesis, trafficking, gating, permeation, and recycling. A case in point is the Long QT syndrome (LQTS), a highly arrhythmogenic disease characterized by an abnormally prolonged QT interval on ECG produced by variants and drugs that interfere with the action potential.
View Article and Find Full Text PDFJ Ultrason
December 2024
Department of Nephrology, General Hospital of Mexico Dr. Eduardo Liceaga, Mexico City, Mexico.
Aim: Our objective was to determine the factors associated with the successful maturation of arteriovenous fistulas during hemodialysis.
Material And Methods: This prospective study included patients treated with hemodialysis and predialysis patients. Clinical, biochemical, sociodemographic, vascular ultrasound mapping, flow-mediated dilatation, and surgical factors were analyzed.
Adv Sci (Weinh)
December 2024
Songshan Lake Materials Laboratory, Dongguan, Guangdong, 523808, China.
Flexoelectric coefficient is a tetradic and its introduction enables centrosymmetric materials to exhibit piezoelectricity. However, the flexoelectric paradigm currently lacks a strategy to effectively tune the strain gradient for optimal electro-mechanical coupling. This study proposes a quantized collision model accessible through ionic irradiation technology to explore the flexoelectricity and precisely modulate the strain gradient.
View Article and Find Full Text PDFJ Am Chem Soc
January 2025
Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore 560012, India.
Photoswitchable molecules with structural flexibility can exhibit a complex ground state potential energy landscape due to the accessibility of multiple metastable states at merely low energy barriers. However, conventional bulk analytical techniques are limited in their ability to probe these metastable ground states and their relative energies. This is partially due to the difficulty of inducing changes in small molecules in their ground state, as they do not respond to external stimuli, such as mechanical force, unless they are incorporated into larger polymer networks.
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