Pharmacologic and supra-pharmacologic doses of hydrocortisone acetate did not effect ultrastructural alteration of chondrocytes in articular cartilage of mature rabbits. Early biomechanical alterations are unaccompanied by ultrastructural cytological changes. Not until advanced biochemical alteration is effected by large, repetitive doses, does the ultrastructural alteration begin.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
WKB ameliorates DSS-induced colitis through inhibiting enteric glial cells activation and altering the intestinal microbiota.
J Transl Med
January 2025
Department of Gastroenterology, Air Force Medical Center, No. 30 Fucheng Road, Haidian District, Beijing, 100142, China.
Background: Inflammatory bowel disease (IBD) is a chronic condition influenced by diet, which affects gut microbiota and immune functions. The rising prevalence of IBD, linked to Western diets in developing countries, highlights the need for dietary interventions. This study aimed to assess the impact of white kidney beans (WKB) on gut inflammation and microbiota changes, focusing on their effects on enteric glial cells (EGCs) and immune activity in colitis.
View Article and Find Full Text PDFAbnormalities in mitochondrial energy metabolism induced by cryopreservation negatively affect goat sperm motility.
Front Vet Sci
January 2025
Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, China.
The motility of sperm decreases following cryopreservation, which is closely associated with mitochondrial function. However, the alterations in mitochondrial metabolism after sperm freezing in goats remain unclear. This experiment aimed to investigate the impact of ultra-low temperature freezing on goat sperm's mitochondrial energy metabolism and its potential correlation with sperm motility.
View Article and Find Full Text PDFAging and MPTP Sensitivity Depend on Molecular and Ultrastructural Signatures of Astroglia and Microglia in Mice Substantia Nigra.
Cell Mol Neurobiol
January 2025
Department of Neurophysiology, National Institute of Mental Health and Neurosciences, Hosur Road, Bengaluru, 560029, India.
Both astroglia and microglia show region-specific distribution in CNS and often maladapt to age-associated alterations within their niche. Studies on autopsied substantia nigra (SN) of Parkinson's disease (PD) patients and experimental models propose gliosis as a trigger for neuronal loss. Epidemiological studies propose an ethnic bias in PD prevalence, since Caucasians are more susceptible than non-whites.
View Article and Find Full Text PDFEffect of sulfinate salt on bonding and polymerization of adhesive to intracoronally bleached dentin.
Sci Rep
January 2025
Department of Operative Dentistry, Faculty of Dentistry, Chulalongkorn University, 34 Henri Dunant Road, Pathumwan, Bangkok, 10330, Thailand.
To evaluate the effect of sulfinate salt on the bond performance of a two-step self-etch adhesive to an intracoronally bleached pulpal dentin surface. Intracoronally bleached bovine teeth were treated with or without sulfinate salt (sulfinate agent (SA): Clearfil DC activator) before 2-SEA (Clearfil SE Bond 2) application, while unbleached teeth served as the control (n = 5 teeth). Microtensile bond strength (µTBS) using the bonded surface area of 1 mm at the crosshead speed of 1 mm/min measurements after 24 h storage and thermocycles (TC), degree of conversion (DC) analyses by Raman spectroscopy (n = 3 teeth), ultrastructure of resin-dentin interface (n = 3 teeth), and intracoronally bleached pulp chamber dentin surface (n = 3 teeth) observations by scanning electron microscopy (SEM) were subsequently performed.
View Article and Find Full Text PDFGold nanoparticles and induction of structural alteration and enhanced oxidative stress in rat lens.
Food Chem Toxicol
January 2025
Department of Histology, Kasr Al-ainy Faculty of Medicine, Cairo University, Egypt. Electronic address:
There is an emerging wide use of nanotechnology in the medical fields. The information regarding distribution and clearance of gold nanoparticles (AuNPs) in the ocular tissue is insufficient. We investigated the cumulative effect of AuNPs on rat lens structure and their effect on the redox state and aquaporin-0 (AQP0) expression.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!