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Introduction: The medial patellofemoral ligament (MPFL) is the main patellar stabilizer in low knee flexion degrees (0-30°). Isolated MPFL reconstruction (MPFLr) is therefore considered the gold standard of surgical procedures for low flexion patellofemoral instabilities (PFIs). Despite excellent clinical results, little is known about the effect of MPFLr on kinematic parameters (KPs) of the patellofemoral joint in vivo.

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The 24-kDa subunit of mitochondrial complex I regulates growth, microsclerotia development, stress tolerance, and virulence in Verticillium dahliae.

BMC Biol

December 2024

State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.

Background: The complete mitochondrial respiratory chain is a precondition for maintaining cellular energy supply, development, and metabolic balance. Due to the evolutionary differentiation of complexes and the semi-autonomy of mitochondria, respiratory chain subunits have become critical targets for crop improvement and fungal control. In fungi, mitochondrial complex I mediates growth and metabolism.

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Rapid assessment of physiological status is a precondition for addressing biological stress in trees so that they may recover. Environmental stress can cause water deficit in plants, while terahertz (THz) spectroscopy is sensitive to changes in aqueous solutions within organisms. This has given the THz sensor a competitive edge for evaluating plant phenotypes, especially under similar environmental stress, if there are existing differences in the corresponding THz information.

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Perfusion Bioreactor Conditioning of Small-diameter Plant-based Vascular Grafts.

Tissue Eng Regen Med

December 2024

Bioengineering Program, Fred DeMatteis School of Engineering and Applied Science, Hofstra University, 229 Science and Innovation Center, Hempstead, NY, 11549, USA.

Article Synopsis
  • Vascular grafts typically made from synthetic materials face issues like thrombosis and intimal hyperplasia, especially in small diameters, prompting research into alternative options such as decellularized plant scaffolds.* -
  • The study developed a novel bioreactor to precondition small-diameter vascular grafts made from decellularized leatherleaf viburnum, simulating physiological conditions to enhance cell density and reduce thrombus formation.* -
  • Results showed that bioreactor conditioning improved the grafts’ endothelial cell density and suture retention while maintaining cell viability, indicating the potential of these plant-based grafts for vascular repair with lower risk of blood clots.*
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Tardigrades are known for their ability to survive extreme conditions. Reports indicate that tardigrade thermal tolerance is enhanced in the desiccated state; however, these reports have almost always used a single tardigrade species and drying/heating methods vary between studies. Using six different species of tardigrades we confirm that desiccation enhances thermal tolerance in tardigrades.

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