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Objective: Parathyroidectomy (PTX) is indicated in primary hyperparathyroidism (PHPT) with osteoporosis or nephrolithiasis. There is not a uniform consensus on the benefit of PTX for nonspecific symptoms, but patient-reported questionnaires have demonstrated improved quality of life (QOL) afterward. This study aimed to evaluate physical activity and sleep after PTX using smartwatch technology.

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Primary hyperparathyroidism (PHPT) is underdiagnosed. Opportunistic imaging-based parathyroid gland assessment is a proposed strategy for identifying patients at increased risk of undiagnosed PHPT. However, whether this approach is likely to identify individuals with clinically significant disease is unknown.

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Association of different obesity indices with nephrolithiasis in community-dwelling older adults.

Obes Res Clin Pract

December 2024

The Persian Gulf Tropical Medicine Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran.

Article Synopsis
  • Obesity is associated with nephrolithiasis (kidney stones), especially in older adults, prompting this study to explore how various obesity-related indices relate to this condition.
  • The study involved 2,419 older adults, analyzing data from the Bushehr Elderly Health program, and found that specific fat distribution ratios were linked to a history of kidney stones.
  • Key findings revealed significant associations between nephrolithiasis and fat ratios, with differences noted between genders—highlighting the importance of monitoring these indices for better health outcomes in the elderly.
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Article Synopsis
  • Coronary artery calcium scoring (CACS) is a non-invasive method that improves cardiovascular risk assessment for individuals without symptoms and is increasingly linked to non-cardiovascular diseases and overall mortality.
  • The review emphasizes a strong connection between CACS and various non-CV diseases like COPD, diabetes, and chronic kidney disease, suggesting CACS could help with early diagnosis and risk evaluation.
  • Further research is needed to determine effective CACS cutoff values and enhance integration of this scoring into healthcare for better preventive care.
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Background: Brown tumors are rare bone manifestations of primary hyperparathyroidism (PHPT) that may occur at different sites either as single or multiple lesions and they can easily be mistaken for malignant lesions. Neither bone site nor morphological or functional imaging are useful to drive the differential diagnosis and biopsy is often the only conclusive procedure.

Case Description: We report the case of a 53 years-old man referred to our outpatient clinic for severe symptomatic PHPT complicated by nephrolithiasis and osteoporosis.

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