Objectives: In previous manometric studies, we observed that micturition was associated with phase III of the migrating motor complex. The present study aimed to objectify this possible relationship and to examine whether modulation of micturition frequency influences migrating motor complex phase III incidence.
Methods: In a retrospective study, ambulatory antroduodenal manometry and micturition data of 27 subjects were analyzed. In a prospective study, antroduodenal motility and micturition patterns were studied in five subjects who were subjected to an oral water load. Volunteers were either allowed to micturate ad libitum or instructed to postpone micturition.
Results: In the retrospective part of the study, a statistically significant association was found between phase III and micturition. Of all micturitions, 50% took place during or within 10 min from phase III. Also, in the prospective part of the study, phase III and micturition, as well as micturition urge, showed a significant association (p < 0.05).
Conclusion: Micturition and phase III of the migrating motor complex are associated in time.
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