AI Article Synopsis

  • Experimental data compares the hemolytic activity of ctx+ Hly- and ctx- Hly+ strains of V. cholerae, revealing how nutrient media influence their growth.
  • Ctx+ strains of both serogroups can produce hemolysin under iron deficiency, effectively lysing sheep red blood cells.
  • Analysis shows that hemolysins from ctx- and ctx+ strains are biologically and immunologically similar despite different conditions.

Article Abstract

Experimental data on the comparative evaluation of the hemolytic activity of ctx+ Hly- and ctx- Hly+ V. cholerae, serogroups O1 and O139, in the process of their cultivation in different nutrient media are presented. The capacity of ctx+ V. cholerae of both serogroups cultivated under the conditions of iron deficiency, for the production of hemolysin capable of lyzing sheep red blood cells was shown. Hemolysin produced by ctx- strains of V. cholerae was synthesized under any conditions. The study of hemolysin preparations obtained from ctx- and ctx+ strains of V. cholerae, serogroups O1 and O139, revealed that they were biologically and immunologically similar.

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