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In order to identify the genes and gene functions that underlie key aspects of legume biology, researchers have selected the cool season legume Medicago truncatula (Mt) as a model system for legume research. A set of >170 000 Mt ESTs has been assembled based on in-depth sampling from various developmental stages and pathogen-challenged tissues. MtDB is a relational database that integrates Mt transcriptome data and provides a wide range of user-defined data mining options. The database is interrogated through a series of interfaces with 58 options grouped into two filters. In addition, the user can select and compare unigene sets generated by different assemblers: Phrap, Cap3 and Cap4. Sequence identifiers from all public Mt sites (e.g. IDs from GenBank, CCGB, TIGR, NCGR, INRA) are fully cross-referenced to facilitate comparisons between different sites, and hypertext links to the appropriate database records are provided for all queries' results. MtDB's goal is to provide researchers with the means to quickly and independently identify sequences that match specific research interests based on user-defined criteria. The underlying database and query software have been designed for ease of updates and portability to other model organisms. Public access to the database is at http://www.medicago.org/MtDB.
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http://dx.doi.org/10.1093/nar/gkg119 | DOI Listing |
Microbiol Res
December 2024
Commonwealth Scientific and Industrial Research Organisation (CSIRO), Agriculture and Food, Acton, ACT, Australia; Commonwealth Scientific and Industrial Research Organisation (CSIRO), Advanced Engineering Biology Future Science Platform, Acton, ACT, Australia; Commonwealth Scientific and Industrial Research Organisation (CSIRO), Microbiomes for One Systems Health Future Science Platform, Acton, ACT, Australia.
The use of multi-omic approaches has significantly advanced the exploration of microbial traits, leading to the discovery of new bioactive compounds and their mechanisms of action. Streptomyces sp. MH71 is known for its antifungal properties with potential for use in crop protection.
View Article and Find Full Text PDFPrev Vet Med
December 2024
Department of Genetics, Animal Breeding and Ethology, Faculty of Animal Science, University of Agriculture in Krakow, al. Mickiewicza 24/28, Krakow 30-059, Poland. Electronic address:
The purpose of the paper was to apply an Artificial Neural Networks with Radial Basis Function to develop an application model for diagnosing a subclinical ketosis type I and II in dairy cattle. While building the neural network model, applied methodology was compatible to the procedures used in Data Mining processes. The data set was created based on the composition of milk samples of 1520 Polish Holstein-Friesian cows.
View Article and Find Full Text PDFHealthc Technol Lett
December 2024
Intelligent Systems Research Centre, School of Computing, Engineering and Intelligent Systems Ulster University, Magee campus Derry∼Londonderry Northern Ireland UK.
Missing Alzheimer's disease (AD) data is prevalent and poses significant challenges for AD diagnosis. Previous studies have explored various data imputation approaches on AD data, but the systematic evaluation of deep learning algorithms for imputing heterogeneous and comprehensive AD data is limited. This study investigates the efficacy of denoising autoencoder-based imputation of missing key features of heterogeneous data that comprised tau-PET, MRI, cognitive and functional assessments, genotype, sociodemographic, and medical history.
View Article and Find Full Text PDFThis paper develops a method for cancer classification from microRNA data using a convolutional neural network (CNN)-based model optimized by genetic algorithm. The convolutional neural network has performed well in various recognition and perception tasks. This paper contributes to the cancer classification using a union of two CNNs.
View Article and Find Full Text PDFBackground And Aims: The rapid expansion of artificial intelligence (AI) within worldwide healthcare systems is occurring at a significant rate. In this context, the Middle East has demonstrated distinctive characteristics in the application of AI within the healthcare sector, particularly shaped by regional policies. This study examined the outcomes resulting from the utilization of AI within healthcare systems in the Middle East.
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