Intestinal and extraintestinal parasitic diseases continue to constitute important public health problems in many developing African countries. While malaria continues to ravage the continent, the silent onslaught of intestinal helminthiases and protozoal infection seem not to relent. The objectives of this study was therefore to determine the prevalence of intestinal helminthic and protozoan infections and to determine the trends in intestinal parasitic infections. Results of laboratory investigations for parasitic infections during a three-year period in two succeeding decades (1988-90 and 1996-98) were analysed. During the two periods 4233 (65.1%) of 6504 and 2297 (63.1%) of 3641 clinical specimens were respectively, positive for intestinal parasites. These results are very significant as determinants of the level of environmental and domiciliary hygiene. It is concluded that the findings should be of great concern to the local Authority Health Departments which should spur the government to concerted effort aimed at ameliorating the deplorable situation brought about by indiscriminate faecal disposal.
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Int J Parasitol Drugs Drug Resist
January 2025
Department of Infectious Diseases, Unit of Foodborne and Neglected Parasitic Diseases, Istituto Superiore di Sanità, viale Regina Elena 299, Rome, Italy. Electronic address:
Giardia duodenalis is a widespread intestinal protozoan that affects mammals, including humans. Symptoms can range from being subclinical to causing severe abdominal pain and diarrhoea. Giardiasis often requires repeated treatment with synthetic drugs like metronidazole.
View Article and Find Full Text PDFParasitol Res
January 2025
Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
In 2010, a Cryptosporidium hominis outbreak resulted in 27,000 clinical cryptosporidiosis cases (45% of the population) in Östersund, Sweden. Long-term abdominal and joint symptoms are common following cryptosporidiosis in adults, and it can affect the development of children in low-income countries. We investigated the potential consequences for children in a high-income setting.
View Article and Find Full Text PDFPathogens
January 2025
Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara 06330, Turkey.
Gastrointestinal nematodes (GINs) inflict significant economic losses on sheep and goat farming globally due to reduced productivity and the development of anthelmintic resistance. Sustainable control strategies are urgently needed including the exploration of medicinal plants as safer alternatives to chemical anthelmintics. This genus of plants is used for anti-inflammatory, antioxidant, and antimicrobial activities.
View Article and Find Full Text PDFAnimals (Basel)
January 2025
Department of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.
and are major parasitic nematodes of dogs. Many environmental and phenological changes have recently modified their geographic patterns in many countries; thus, this study has updated the distribution of and in dog populations of selected regions of Central and Southern Italy. Also, collateral data on other endoparasites affecting the study population have been collected.
View Article and Find Full Text PDFVet Res
January 2025
Laboratory of Helminth Parasites of Zoonotic Importance (ATENEA), Institute of Natural Resources and Agrobiology of Salamanca (IRNASA-CSIC), Salamanca, Spain.
Plasmin, the final product of fibrinolysis, is a broad-spectrum serine protease that degrades extracellular matrix (ECM) components, a function exploited by multiple pathogens for dissemination purposes. The trematode Fasciola hepatica is the leading cause of fasciolosis, a major disease of livestock and an emerging zoonosis in humans. Infection success depends on the ability of F.
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