1) Leucine aminopeptidase (LAP) was determined in maternal and fetal blood and in the placenta of mild and severe pre-eclamptic patients, then compared to the levels of normal pregnancy. 2) The enzyme activity increased significantly in severe pre-eclampsia as compared with the mild type and with normal pregnancy. 3) In mild pre-eclamptic patients LAP activity of maternal and cord blood did not increase significantly as compared with the normal cases but the placenta showed a slight decrease. 4) The enzyme level in cord blood did not increase markedly in pre-eclampsia.

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http://dx.doi.org/10.3109/00016347609156782DOI Listing

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