[Content of calretinin-immunoreactive epitheliocytes of the stomach in patients with chronic gastritis and peptic ulcer].

The article covers the information about 50 patients with gastric ulcer (GU) and 110 patients with duodenal ulcer (DU). 60 healthy persons and 70 patients with chronic helicobacter gastritis (CHG) formed comparative groups. Calretinin-immunoreactive epitheliocytes in antral region's gastric mucous membrane were reaved by clinical-endoscopic morphological and immunohistochemical investigations. It is shown that hyperplasia of calretinin-immunoreactive cells is in CHG cases. On the contrary, in DU and GU there is hypoplasia of calretinin-immunoreactive cells. Diametrically opposed data on quantitative description of focused endocrine cells in patients with CHG and peptic ulcer disease permitted to make a conclusion about the importance of calretinin-immunoreactive cells in peptic ulcer. The results of the investigation made it possible to give the prognostic appreciation of CHG course and its transformation into peptic ulcer disease.