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Physiologic insulin resensitization lowers cost in patients with diabetes and kidney disease.
Am J Manag Care
January 2025
McGovern Medical School at UTHealth Houston, 4513 Teas St, Bellaire, TX 77401.
Objective: To examine the effect of physiologic insulin resensitization (PIR) on the cost of treating patients with diabetes and chronic kidney disease (CKD).
Study Design: The mean 1-year cost of treating 66 Medicare Advantage patients with diabetes and CKD who were receiving PIR was compared with that of treating 1301 Medicare Advantage patients with diabetes and CKD not receiving PIR. Differences in disease severity were compared using mean risk adjustment factor scores.
Evaluating the Acceptance and Usability of an Independent, Noncommercial Search Engine for Medical Information: Cross-Sectional Questionnaire Study and User Behavior Tracking Analysis.
JMIR Hum Factors
January 2025
Institute of General Practice, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Background: The internet is a key source of health information, but the quality of content from popular search engines varies, posing challenges for users-especially those with low health or digital health literacy. To address this, the "tala-med" search engine was developed in 2020 to provide access to high-quality, evidence-based content. It prioritizes German health websites based on trustworthiness, recency, user-friendliness, and comprehensibility, offering category-based filters while ensuring privacy by avoiding data collection and advertisements.
View Article and Find Full Text PDFEvaluation of the effect of the water-energy nexus on the performance of the water-energy supply system.
Environ Sci Pollut Res Int
January 2025
Department of Civil Engineering, University of Qom, Qom, Iran.
In this study, the water-energy nexus is investigated throughout coupling the Water Evaluation and Planning (WEAP) and Low Emission Analysis Platform (LEAP) models under the climate change effects in the Marun basin, Iran. For this purpose, first, the climate change effects on water resources and consumption nodes are calculated under representative concentration pathway (RCP) scenarios from the fifth report of the International Panel on Climate Change (IPCC). Artificial neural network (ANN) is used to model river inflow and Cropwat model is used for agricultural water demand in future time (2015-2040).
View Article and Find Full Text PDFThe GacS/GacA two-component system strongly regulates antimicrobial competition mechanisms of MFE01 strain.
J Bacteriol
January 2025
Laboratoire de Communication Bactérienne et Stratégies Anti-infectieuses (CBSA UR4312, formerly LMSM EA4312), Univ Rouen Normandie, Université Caen Normandie, Normandie Univ, Rouen, France.
Unlabelled: MFE01 is an environmental bacterium characterized by an hyperactive type 6 secretion system (T6SS) and a strong emission of volatile organic compounds (VOCs). In a previous study, a transposition mutant, 3H5, exhibited an inactive T6SS and altered VOC emission. In 3H5, the interruption of gene by the transposon was insufficient to explain these phenotypes.
View Article and Find Full Text PDFHope for the best, but prepare for the worst - Diagnostic accuracy of the American College of Surgeons National Surgical Quality Improvement Program - Risk model for patients undergoing abdominoplasty after massive weight loss - Results from a Retrospective Cohort Study.
JPRAS Open
March 2025
Department of Orthopaedic, Trauma and Plastic Surgery, University Hospital Leipzig, 04103 Leipzig, Germany.
Background: This study aimed to validate the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) risk calculator for predicting outcomes in patients undergoing abdominoplasty after massive weight loss.
Methods: Patients' characteristics, pre-existing comorbidities and adverse outcomes in our department from 2013 to 2023 were collected retrospectively. Adverse events were defined according to ACS-NSQIP standards and predicted risks were calculated manually using the ACS-NSQIP risk calculator.
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