Objective: To observe the effect of extract from overground part of Trpterygium wilfordii on Masugi nephritis in rabbits.

Method: Masugi nephritis was made by giving i.v. the rabbit an injection of sheep antirabbit serum.

Result: The extract could effectively inhibit the increase of uric protein, serum BUN, creatinine and glomerulus cells in rabbits.

Conclusion: The extract from overground part of Tripterygium wilfordii has better curative effect on Masugi nephritis in rabbits.

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